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Name :
Active Recombinant Human FGFR3, Fc Chimera

Specification :
| Source : Mammalian cells | Species : Human | Tag : Fc Chimera | Predicted N Terminal : Glu23 | Form : Lyophilized from a 0.2 µm filtered solution in PBS. | Bio-activity : Measured by its ability to inhibit FGF acidic-dependent proliferation of NR6R-3T3 mouse fibroblast cells.The ED50 for this effect is typically 0.03 – 0.12 µg/mL. | Molecular Mass : Recombinant Human FGFR3, Fc Chimera has a calculated MW of 65 kDa (monomer). In SDS-PAGE migrates as 90-100 kDa, reducing conditions. | Purity : >90%, by SDS-PAGE under reducing conditions and visualized by silver stain. | Storage : Avoid repeated freeze-thaw cycles. No activity loss was observed after storage at: In lyophilized state for 1 year (4ºC); After reconstitution under sterile conditions for 3 months (-70ºC).

Gene Information :
| Gene Name : FGFR3 fibroblast growth factor receptor 3 [ Homo sapiens ] | Official Symbol : FGFR3 | Synonyms : FGFR3; fibroblast growth factor receptor 3; ACH, achondroplasia, thanatophoric dwarfism; CD333; CEK2; JTK4; FGFR-3; tyrosine kinase JTK4; hydroxyaryl-protein kinase; ACH; HSFGFR3EX; | Gene ID : 2261 | mRNA Refseq : NM_000142 | Protein Refseq : NP_000133 | MIM : 134934 | UniProt ID : P22607 | Chromosome Location : 4p16.3

MedChemExpress (MCE) recombinant proteins include: cytokines, enzymes, growth factors, hormones, receptors, transcription factors, antibody fragments, etc. They are often essential for supporting cell growth, stimulating cell signaling pathways, triggering or inhibiting cell differentiation; and are useful tools for elucidating protein structure and function, understanding disease onset and progression, and validating pharmaceutical targets. At MedChemExpress (MCE), we strive to provide products with only the highest quality. Protein identity, purity and biological activity are assured by our robust quality control and assurance procedures.
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Author: Cholesterol Absorption Inhibitors