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Name :
Recombinant Human ICAM3 Protein, Myc/DDK-tagged, C13 and N15-labeled

Specification :
| Description : The protein encoded by this gene is a member of the intercellular adhesion molecule (ICAM) family. All ICAM proteins are type I transmembrane glycoproteins, contain 2-9 immunoglobulin-like C2-type domains, and bind to the leukocyte adhesion LFA-1 protein. This protein is constitutively and abundantly expressed by all leucocytes and may be the most important ligand for LFA-1 in the initiation of the immune response. It functions not only as an adhesion molecule, but also as a potent signalling molecule. Alternative splicing results in multiple transcript variants encoding different isoforms. | Source : HEK293 | Species : Human | Tag : Myc/DDK | Molecular Mass : 59.5 kDa | AA Sequence : MATMVPSVLWPRACWTLLVCCLLTP GVQGQEFLLRVEPQNPVLSAGGSLF VNCSTDCPSSEKIALETSLSKELVA SGMGWAAFNLSNVTGNSRILCSVYC NGSQITGSSNITVYRLPERVELAPL PPWQPVGQNFTLRCQVEDGSPRTSL TVVLLRWEEELSRQPAVEEPAEVTA TVLASRDDHGAPFSCRTELDMQPQG LGLFVNTSAPRQLRTFVLPVTPPRL VAPRFLEVETSWPVDCTLDGLFPAS EAQVYLALGDQMLNATVMNHGDTLT ATATATARADQEGAREIVCNVTLGG ERREARENLTVFSFLGPIVNLSEPT AHEGSTVTVSCMAGARVQVTLDGVP AAAPGQPAQLQLNATESDDGRSFFC SATLEVDGEFLHRNSSVQLRVLYGP KIDRATCPQHLKWKDKTRHVLQCQA RGNPYPELRCLKEGSSREVPVGIPF FVNVTHNGTYQCQASSSRGKYTLVV VMDIEAGSSHFVPVFVAVLLTLGVV TIVLALMYVFREHQRSGSYHVREES TYLPLTSMQPTEAMGEEPSRAETRT RPLEQKLISEEDLAANDILDYKDDD DKV | Purity : > 80% as determined by SDS-PAGE and Coomassie blue staining | Stability : Stable for 3 months from receipt of products under proper storage and handling conditions. | Storage : Store at -80 centigrade. Avoid repeated freeze-thaw cycles. | Concentration : 50 μg/mL as determined by BCA | Storage Buffer : 100 mM glycine, 25 mM Tris-HCl, pH 7.3.

Gene Information :
| Gene Name : ICAM3 intercellular adhesion molecule 3 [ Homo sapiens (human) ] | Official Symbol : ICAM3 | Synonyms : ICAM3; intercellular adhesion molecule 3; CD50; CDW50; ICAM R; ICAM-3; intercellular adhesion molecule-3; ICAM-R; | Gene ID : 3385 | mRNA Refseq : NM_002162 | Protein Refseq : NP_002153 | MIM : 146631 | UniProt ID : P32942

MedChemExpress (MCE) recombinant proteins include: cytokines, enzymes, growth factors, hormones, receptors, transcription factors, antibody fragments, etc. They are often essential for supporting cell growth, stimulating cell signaling pathways, triggering or inhibiting cell differentiation; and are useful tools for elucidating protein structure and function, understanding disease onset and progression, and validating pharmaceutical targets. At MedChemExpress (MCE), we strive to provide products with only the highest quality. Protein identity, purity and biological activity are assured by our robust quality control and assurance procedures.
Related category websites: https://www.medchemexpress.com/recombinant-proteins.html
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Author: Cholesterol Absorption Inhibitors