Name :
Recombinant Human ICAM4 Protein, Myc/DDK-tagged, C13 and N15-labeled
Specification :
| Description : This gene encodes the Landsteiner-Wiener (LW) blood group antigen(s) that belongs to the immunoglobulin (Ig) superfamily, and that shares similarity with the intercellular adhesion molecule (ICAM) protein family. This ICAM protein contains 2 Ig-like C2-type domains and binds to the leukocyte adhesion LFA-1 protein. The molecular basis of the LW(A)/LW(B) blood group antigens is a single aa variation at position 100; Gln-100=LW(A) and Arg-100=LW(B). Alternative splicing results in multiple transcript variants encoding distinct isoforms. | Source : HEK293 | Species : Human | Tag : Myc/DDK | Molecular Mass : 29.6 kDa | AA Sequence : MGSLFPLSLLFFLAAAYPGVGSALG RRTKRAQSPKGSPLAPSGTSVPFWV RMSPEFVAVQPGKSVQLNCSNSCPQ PQNSSLRTPLRQGKTLRGPGWVSYQ LLDVRAWSSLAHCLVTCAGKTRWAT SRITAYSVPGGLLGGDPEAWKPGHL FRKPGALHRPGSGQRDLDLRVCCWT PRLLAARDLPRAPQSRRPGGPQQLG THYTDARLEPRAHSFGLRFHRCPCR DPPHCGRCVPMQVPSYEVPGVKGDV LCRLSEKKRNMKQSGEMAIHGGTRT RPLEQKLISEEDLAANDILDYKDDD DKV | Purity : > 80% as determined by SDS-PAGE and Coomassie blue staining | Stability : Stable for 3 months from receipt of products under proper storage and handling conditions. | Storage : Store at -80 centigrade. Avoid repeated freeze-thaw cycles. | Concentration : 50 μg/mL as determined by BCA | Storage Buffer : 100 mM glycine, 25 mM Tris-HCl, pH 7.3.
Gene Information :
| Gene Name : ICAM4 intercellular adhesion molecule 4 (Landsteiner-Wiener blood group) [ Homo sapiens (human) ] | Official Symbol : ICAM4 | Synonyms : ICAM4; intercellular adhesion molecule 4 (Landsteiner-Wiener blood group); intercellular adhesion molecule 4 (LW blood group), intercellular adhesion molecule 4, Landsteiner Wiener blood group, Landsteiner Wiener blood group, LW; intercellular adhesion molecule 4; CD242; CD242 antigen; LW blood group protein; Landsteiner-Wiener blood group antigen a; Landsteiner-Wiener blood group glycoprotein; intercellular adhesion molecule 4 (LW blood group); LW; | Gene ID : 3386 | mRNA Refseq : NM_001039132 | Protein Refseq : NP_001034221 | MIM : 614088 | UniProt ID : Q14773
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