Recombinant Human ICOS, Fc-tagged

Specification :
| Description : CD278, also called inducible costimulator (ICOS) or CRP1 (CD28-related protein-1), is a member of the growing CD28 family of immune costimulatory receptors. Other family members are CD28, CTLA-4 and PD-1. ICOS is expressed on most CD45RO+ cells. ICOS expression is upregulated within approximately 24-48 hours of activation on Th primed cells. B7-H2, a member of the B7 family of costimulatory ligands, has been identified as the ICOS ligand. The B7-H2/ICOS interaction appears to play roles in T cell dependent B cell activation and Th differentiation. | Source : CHO Cells | Species : Human | Tag : Fc | Form : Lyophilized from 0.2μm-filtered solution in PBS. | Purity : ≥98% (SDS-PAGE) | Stability : Stable for at least 1 year after receipt when stored at -20°C. Working aliquots are stable for up to 3 months when stored at -20°C. | Storage : Short Term Storage: +4°C; Long Term Storage: -20°C. Avoid freeze/thaw cycles.