Recombinant Human IFNGR1 Protein, His-tagged

Specification :
| Description : IFNGR1, also known as interferon gamma receptor 1, is a member of the hematopoietic cytokine receptor superfamily. It is a receptor that binds interferon-γ, the sole member of interferon type II. It induces the rapid dimerization of chains, thereby forming a site that is recognized by the extracellular domain of IFNGR2. It is expressed in a membrane-bound form in many cell types, and is over-expressed in tumour cells. Its signaling promotes autoimmune germinal centers via cell-intrinsic induction of BCL-6. It is crucial for host defence against mycobacterial infections. It is associated with susceptibility to pulmonary tuberculosis (TB). | Source : Insect cell | Species : Human | Tag : His | Form : Liquid | Molecular Mass : 26.6 kDa | AASequence : EMGTADLGPSSVPTPTNVTIESYNM NPIVYWEYQIMPQVPVFTVEVKNYG VKNSEWIDACINISHHYCNISDHVG DPSNSLWVRVKARVGQKESAYAKSE EFAVCRDGKIGPPKLDIRKEEKQIM IDIFHPSVFVNGDEQEVDYDPETTC YIRVYNVYVRMNGSEIQYKILTQKE DDCDEIQCQLAIPVSSLNSQYCVSA EGVLHVWGVTTEKSKEVCITIFNSS IKGHHHHHH | N-terminal Sequence Analysis : Glu 18 | Endotoxin : | Purity : > 90% by SDS – PAGE | Storage : Can be stored at +4 centigrade short term (1-2 weeks). For long term storage, aliquot and store at -20 centigrade or -70 centigrade. Avoid repeated freezing and thawing cycles. | Concentration : 1.0 mg/mL (determined by Absorbance at 280nm) | Storage Buffer : In Phosphate Buffered Saline (pH 7.4) containing 10% glycerol. | Warning : For research use only. This product is not intended or approved for human, diagnostics or veterin