Name :
Active Recombinant Human FGFR4, Fc-tagged, Biotinylated
Specification :
| Source : Human cells | Species : Human | Tag : Fc | Form : Supplied at 0.5 mg/ml in sterile PBS pH7.4 (carrier free). The purified recombinant protein was labeled with Biotin (3-5 Biotin per molecule) | Bio-activity : Binds and inhibits aFGF / FGF-acidic dependent proliferation of mouse fibroblast cells with an ED50 of 0.01 – 0.05 μg/ml | Molecular Mass : Calculated molecular mass (kDa): 64.1; Estimated by SDS-PAGE under reducing condition (kDa): 75-85 | AA Sequence : LEASEEVELEPCLAPSLEQQEQELT VALGQPVRLCCGRAERGGHWYKEGS RLAPAGRVRGWRGRLEIASFLPED AGRYLCLARGSMIVLQNLTLITGDS LTSSNDDEDPKSHRDPSNRHSYPQQ APYWTHPQRMEKKLHAVPAGNTVK FRCPAAGNPTPTIRWLKDGQAFHGE NRIGGIRLRHQHWSLVMESVVPSDR GTYTCLVENAVGSIRYNYLLDVLE RSPHRPILQAGLPANTTAVVGSDVE LLCKVYSDAQPHIQWLKHIVINGSS FGADGFPYVQVLKTADINSSEVEV LYLRNVSAEDAGEYTCLAGNSIGLS YQSAWLTVLPEEDPTWTAAAPEARY TDGSTGTHTCPPCPAPELLGGPSV FLFPPKPKDTLMISRTPEVTCVVVD VSHEDPEVKFNWYVDGVEVHNAKTK PREEQYNSTYRVVSVLTVLHQDWL NGKEYKCKVSNKALPAPIEKTISKA KGQPREPQVYTLPPSREEMTKNQVS LTCLVKGFYPSDIAVEWESNGQPE NNYKTTPPVLDSDGSFFLYSKLTVD KSRWQQGNVFSCSVMHEALHNHYTQ KSLSLSPGK | Endotoxin : | Purity : >95% judged by SDS-PAGE under reducing condition | Storage : The product is shipped at 4°C. Upon receipt, centrifuge the product briefly before opening the vial. It is recommended to store small aliquots at the temperature below –20°C for long-term storage and the product is stable for 3 months. The undiluted protein can be stored at 4°C for no more than 2 weeks. Avoid repeated freeze-thaw cycles.
Gene Information :
| Gene Name : FGFR4 fibroblast growth factor receptor 4 [ Homo sapiens ] | Official Symbol : FGFR4 | Synonyms : FGFR4; fibroblast growth factor receptor 4; CD334; JTK2; FGFR-4; tyrosylprotein kinase; protein-tyrosine kinase; hydroxyaryl-protein kinase; tyrosine kinase related to fibroblast growth factor receptor; TKF; MGC20292; | Gene ID : 2264 | mRNA Refseq : NM_002011 | Protein Refseq : NP_002002 | MIM : 134935 | UniProt ID : P22455 | Chromosome Location : 5q33-qter | Pathway : Downstream signaling of activated FGFR, organism-specific biosystem; Endocytosis, organism-specific biosystem; Endocytosis, conserved biosystem; FGF signaling pathway, organism-specific biosystem; FGFR ligand binding and activation, organism-specific biosystem; FGFR4 ligand binding and activation, organism-specific biosystem; FRS2-mediated cascade, organism-specific biosystem; | Function : ATP binding; fibroblast growth factor 1 binding; fibroblast growth factor 2 binding; fibroblast growth factor binding; fibroblast growth factor-activated receptor activity; fibroblast growth factor-activated receptor activity; heparin binding; nucleotide binding; protein tyrosine kinase activity; receptor activity;
Related category websites: https://www.medchemexpress.com/recombinant-proteins.html
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