Recombinant Human IGF1R Protein, MYC/DDK-tagged

Specification :
| Description : This receptor binds insulin-like growth factor with a high affinity. It has tyrosine kinase activity. The insulin-like growth factor I receptor plays a critical role in transformation events. Cleavage of the precursor generates alpha and beta subunits. It is highly overexpressed in most malignant tissues where it functions as an anti-apoptotic agent by enhancing cell survival. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, May 2014]. | Source : HEK293 | Species : Human | Tag : MYC/DDK | Form : 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol. | Molecular Mass : 81 kDa | Purity : >50 ug/mL as determined by microplate BCA method | Concentration : >50 ug/mL as determined by microplate BCA method