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Name :
Recombinant Human CD47 protein, T7/His-tagged

Specification :
| Source : E. coli | Species : Human | Tag : T7/His | Form : 0.5 mg/ml, sterile-filtered, in 20 mM pH 8.0 Tris-HCl Buffer, with proprietary formulation of NaCl, KCl, EDTA, arginine, DTT and Glycerol. | AA Sequence : MASMTGGQQMGRGHHHHHHENLYFQ GGEFQLLFNKTKSVEFTFCNDTVVI PCFVTNMEAQNTTEVYVKWKFKGRD IYTFDGALNKSTVPTDFSSAKIEVS QLLKGDASLKMDKSDAVSHTGNYTC EVTELTREGETII | Purity : >90% by SDS-PAGE | Applications : 1. May be used for in vitro non-glycosylated CD47 longest extracellular domain protein mediated “don”t eat me” signal regulation study for cancer cell imgration, T cell activation et al. with this protein as either coating matrix protein or soluble factor.2. May be used as CD47 protein-protein interaction assay.3. As enzymatic substrate for various proteases.4. As potential cancer diagnostic biomarker protein.5. As antigen for specific antibody production. | Storage : Keep at -80centigrade for long term storage. Product is stable at 4 centigrade for at least 30 days.

Gene Information :
| Gene Name : CD47 CD47 molecule [ Homo sapiens ] | Official Symbol : CD47 | Synonyms : CD47; CD47 molecule; CD47 antigen (Rh related antigen, integrin associated signal transducer) , MER6; leukocyte surface antigen CD47; antigen identified by monoclonal 1D8; antigenic surface determinant protein OA3; CD47 glycoprotein; IAP; integrin assoc | Gene ID : 961 | mRNA Refseq : NM_001777 | Protein Refseq : NP_001768 | MIM : 601028 | UniProt ID : Q08722 | Chromosome Location : 3q13.1-q13.2 | Pathway : Cell surface interactions at the vascular wall, organism-specific biosystem; Cell-Cell communication, organism-specific biosystem; ECM-receptor interaction, organism-specific biosystem; ECM-receptor interaction, conserved biosystem; Hemostasis, organism-specific biosystem | Function : protein binding; thrombospondin receptor activity;

MedChemExpress (MCE) recombinant proteins include: cytokines, enzymes, growth factors, hormones, receptors, transcription factors, antibody fragments, etc. They are often essential for supporting cell growth, stimulating cell signaling pathways, triggering or inhibiting cell differentiation; and are useful tools for elucidating protein structure and function, understanding disease onset and progression, and validating pharmaceutical targets. At MedChemExpress (MCE), we strive to provide products with only the highest quality. Protein identity, purity and biological activity are assured by our robust quality control and assurance procedures.
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Author: Cholesterol Absorption Inhibitors