Recombinant Human CD53 Protein, His-tagged

Specification :
| Description : The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is a cell surface glycoprotein that is known to complex with integrins. It contributes to the transduction of CD2-generated signals in T cells and natural killer cells and has been suggested to play a role in growth regulation. Familial deficiency of this gene has been linked to an immunodeficiency associated with recurrent infectious diseases caused by bacteria, fungi and viruses. Alternative splicing results in multiple transcript variants. | Source : Human Cells | Species : Human | Tag : His | Form : Purified protein formulated in a sterile solution of TBS buffer, pH7.141, without any preservatives. | Molecular Mass : 24.2 kDa | Endotoxin : Endotoxin level is | Purity : >90% by SDS-PAGE gel and Coomassie Blue staining | Applications : Antigens, Western, ELISA and other in vitro binding or in vivo functional assays, and protein-protein interaction studies.