Recombinant Human CD6 Molecule, His-tagged

Specification :
| Cat. No. : CD6-4759H | Description : CD6 (Cluster of Differentiation 6) is a cell surface glycoprotein that is involved in T cell activation and a member of the scavenger receptor cysteine rich protein superfamily (SRCRSF). CD6 is expressed at low levels on immature thymocytes and at high levels on mature thymocytes. CD6 appears to play a role as both a costimulatory molecule in T cell activation and as an adhesion receptor. Studies demonstrating a mitogenic effect for T cells with some CD6 specific monoclonal antibodies, in conjunction with either accessory cells or PMA and antiCD2 mAb, support the concept of CD6 as a co stimulatory molecule. | Source : Recombinant human CD6 /TP120 His18 -Glu398 (Accession Q8WWJ7) fused with a C-terminal His tag was produced in human HEK293 cells | Species : Human | Form : Bulk protein in a 0.22 μm filtered solution of PBS, pH7.4 and delivered as liquid formulation or lyophilized powder. Normally 5-8% trehalose and mannitol are added as protectants before lyophilization. | Purity : >95% as determined by SDS-PAGE. All lots are greater than 95% pure. | Endotoxin : Less than 1.0 EU per 1 μg of the rhCD6 by the LAL method. | Storage : Store at -80°C upon received. Avoid repeated freeze-thaw cycles.