Recombinant Human CD63 Protein (103-203 aa), His-sumostar-tagged

Specification :
| Description : Functions as cell surface receptor for TIMP1 and plays a role in the activation of cellular signaling cascades. Plays a role in the activation of ITGB1 and integrin signaling, leading to the activation of AKT, FAK/PTK2 and MAP kinases. Promotes cell survival, reorganization of the actin cytoskeleton, cell adhesion, spreading and migration, via its role in the activation of AKT and FAK/PTK2. Plays a role in VEGFA signaling via its role in regulating the internalization of KDR/VEGFR2. Plays a role in intracellular vesicular transport processes, and is required for normal trafficking of the PMEL luminal domain that is essential for the development and maturation of melanocytes. Plays a role in the adhesion of leukocytes onto endothelial cells via its role in the regulation of SELP trafficking. May play a role in mast cell degranulation in response to Ms4a2/FceRI stimulation, but not in mast cell degranulation in response to other stimuli. | Source : Yeast | Species : Human | Tag : His-sumostar | Form : Tris-based buffer,50% glycerol | Molecular Mass : 27.5 kDa | Protein length : 103-203 aa | AA Sequence : AGYVFRDKVMSEFNNNFRQQMENYP KNNHTASILDRMQADFKCCGAANYT DWEKIPSMSKNRVPDSCCINVTVGC GINFNEKAIHKEGCVEKIGGWLRKN V | Purity : > 85% as determined by SDS-PAGE. | Notes : Repeated freezing and thawing is not recommended. Store working aliquots at 4 centigrade for up to one week. | Storage : The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20 centigrade/-80 centigrade. The shelf life of lyophilized form is 12 months at -20 centigrade/-80 centigrade. | Concentration : A hardcopy of COA will be sent along with the products. Please refer to it for detailed information.