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Name :
Recombinant Human CD63 protein, His & GST-tagged

Specification :
| Description : The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. The encoded protein is a cell surface glycoprotein that is known to complex with integrins. It may function as a blood platelet activation marker. Deficiency of this protein is associated with Hermansky-Pudlak syndrome. Also this gene has been associated with tumor progression. Alternative splicing results in multiple transcript variants encoding different protein isoforms. | Source : E. coli | Species : Human | Tag : His & GST | Form : Freeze-dried powder | Molecular Mass : Predicted Molecular Mass: 43.9kDa. | Protein length : Ala103~Val203 (Accession # P08962) | Endotoxin : | Purity : >95% | Characteristic : The isoelectric point is 6.9. | Applications : SDS-PAGE; WB; ELISA; IP. | Stability : The thermal stability is described by the loss rate of the target protein. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. (Referring from China Biological Products Standard, which was calculated by the Arrhenius equation.) The loss of this protein is less than 5% within the expiration date under appropriate storage condition. | Storage : Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months. | Storage buffer : Supplied as lyophilized form in PBS, pH7.4, containing 5% sucrose, 0.01% sarcosyl. | Reconstitution : Reconstitute in sterile PBS, pH7.2-pH7.4.

Gene Information :
| Gene Name : CD63 CD63 molecule [ Homo sapiens (human) ] | Official Symbol : CD63 | Synonyms : MLA1; ME491; LAMP-3; OMA81H; TSPAN30; CD63 antigen (melanoma 1 antigen); granulophysin; lysosomal-associated membrane protein 3; lysosome-associated membrane glycoprotein 3; melanoma-associated antigen ME491; melanoma-associated antigen MLA1; ocular melanoma-associated antigen; tetraspanin-30; tspan-30; CD63 antigen | Gene ID : 967 | mRNA Refseq : NM_001257389.1 | Protein Refseq : NP_001244318.1 | UniProt ID : P08962

MedChemExpress (MCE) recombinant proteins include: cytokines, enzymes, growth factors, hormones, receptors, transcription factors, antibody fragments, etc. They are often essential for supporting cell growth, stimulating cell signaling pathways, triggering or inhibiting cell differentiation; and are useful tools for elucidating protein structure and function, understanding disease onset and progression, and validating pharmaceutical targets. At MedChemExpress (MCE), we strive to provide products with only the highest quality. Protein identity, purity and biological activity are assured by our robust quality control and assurance procedures.
Related category websites: https://www.medchemexpress.com/recombinant-proteins.html
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Author: Cholesterol Absorption Inhibitors