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Name :
Recombinant Human CD79b molecule, immunoglobulin-associated beta, His-tagged

Specification :
| Description : CD79B, also known as Igb and B29, is a 36 kDa transmembrane glycoprotein in the immunoglobulin superfamily. Heterodimers of CD79A and CD79B associate with a membrane bound immunoglobulin on the B cell surface to form the B cell antigen receptor complex(BCR). CD79A and CD79B are required for BCR-mediated signaling and consequently for the development and activation of B lineage cells. Recombinant human CD79B protein, fused to His-tag at N-terminus, was expressed in E.coli. | Source : E.coli | Species : Human | Tag : His-tag | Form : Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 2M UREA, 10% glycerol | Molecular Mass : 17.7 kDa (155aa) | AA Sequence : MGSSHHHHHH SSGLVPRGSH MGSMARSEDR YRNPKGSACS RIWQSPRFIA RKRGFTVKMH CYMNSASGNV SWLWKQEMDE NPQQLKLEKG RMEESQNESL ATLTIQGIRF EDNGIYFCQQ KCNNTSEVYQ GCGTELRVMG FSTLAQLKQR NTLKD | Purity : >90% by SDS – PAGE | Storage : Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles. | Concentration : 1 mg/ml (determined by Bradford assay)

Gene Information :
| Gene Name : CD79B CD79b molecule, immunoglobulin-associated beta [ Homo sapiens ] | Official Symbol : CD79B | Synonyms : CD79B; CD79b molecule, immunoglobulin-associated beta; CD79B antigen (immunoglobulin associated beta) , IGB; B-cell antigen receptor complex-associated protein beta chain; B29; Ig-beta; B-cell-specific glycoprotein B29; immunoglobulin-associated B29 protein; CD79b antigen (immunoglobulin-associated beta); IGB; AGM6; | Gene ID : 974 | mRNA Refseq : NM_000626 | Protein Refseq : NP_000617 | MIM : 147245 | UniProt ID : P40259 | Chromosome Location : 17q23 | Pathway : Adaptive Immune System, organism-specific biosystem; Antigen Activates B Cell Receptor Leading to Generation of Second Messengers, organism-specific biosystem; B Cell Receptor Signaling Pathway, organism-specific biosystem; B cell receptor signaling pathway, organism-specific biosystem; B cell receptor signaling pathway, conserved biosystem; BCR signaling pathway, organism-specific biosystem; Immune System, organism-specific biosystem; | Function : transmembrane signaling receptor activity;

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Author: Cholesterol Absorption Inhibitors