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Name :
Recombinant Human CD80, Fc-tagged

Specification :
| Description : The protein encoded by this gene is a membrane receptor that is activated by the binding of CD28 or CTLA-4. The activated protein induces T-cell proliferation and cytokine production. This protein can act as a receptor for adenovirus subgroup B and may play a role in lupus neuropathy. | Conjugation : Fc | Tissue specificity : Expressed on activated B-cells, macrophages and dendritic cells. | Form : Liquid | Purity : Protein A purified | Storage buffer : Preservative: NoneConstituents: PBS, pH 7.2 | Storage : Aliquot and store at -80°C. Avoid repeated freeze / thaw cycles. | Sequences of amino acids : MGHTRRQGTSPSKCPYLNFFQLLVLAGLSHFCSGVIHVTK EVKEVATLSCGHNVSVEELAQTRIYWQKEKKMVLTMMSGD MNIWPEYKNRTIFDITNNLSIVILALRPSDEGTYECVVLK YEKDAFKREHLAEVTLSVKADFPTPSISDFEIPTSNIRRI ICSTSGGFPEPHLSWLENGEELNAINTTVSQDPETELYAV SSKLDFNMTTNHSFMCLIKYGHLRVNQTFNWNTTKQEHFP DDKTHTCPPCPAPELLGGPSVFLFPPKPKDTLMISRTPEV TCVVVDVSHEDPEVKFNWYVDGVEVHNAKTKPREEQYNST YRVVSVLTVLHQDWLNGKEYKCKVSNKALPAPIEKTISKA KGQPREPQVYTLPPSRDELTKNQVSLTCLVKGFYPSDIAV EWESNGQPENNYKTTPPVLDSDGSFFLYSKLTVDKSRWQQ GNVFSCSVMHEALHNHYTQKSLSLSPGKExtracel lular domain (amino acids 1-241) of human B7.1 sequence is underlined.Human Fc sequence is in italics. | Sequence Similarities : Contains 1 Ig-like C2-type (immunoglobulin-like) domain.Contains 1 Ig-like V-type (immunoglobulin-like) domain.

Gene Information :
| Gene Name : CD80 CD80 molecule [ Homo sapiens ] | Official Symbol : CD80 | Synonyms : CD80; CD80 molecule; CD28LG, CD28LG1, CD80 antigen (CD28 antigen ligand 1, B7 1 antigen) , CD80 molecule; T-lymphocyte activation antigen CD80; B lymphocyte activation antigen B7; B7 1; B7.1; | Gene ID : 941 | mRNA Refseq : NM_005191 | Protein Refseq : NP_005182 | MIM : 112203 | Uniprot ID : P33681 | Chromosome Location : 3q13.3-q21 | Pathway : Adaptive Immune System, organism-specific biosystem; Allograft rejection, organism-specific biosystem; Allograft rejection, conserved biosystem; Autoimmune thyroid disease, organism-specific biosystem; Autoimmune thyroid disease, conserved biosystem; | Function : coreceptor activity; protein binding; receptor activity;

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Author: Cholesterol Absorption Inhibitors