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Name :
Recombinant Human CD80, GST-tagged

Specification :
| Description : The protein encoded by this gene is a membrane receptor that is activated by the binding of CD28 or CTLA-4. The activated protein induces T-cell proliferation and cytokine production. This protein can act as a receptor for adenovirus subgroup B and may play a role in lupus neuropathy. | Source : E.coli | Species : Human | Tag : GST | Protein length : 36-228a.a. | Storage : The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles. | Storage Buffer : 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 100mM GSH and 1% Triton X-100,15%glycerol.

Gene Information :
| Gene Name : CD80 CD80 molecule [ Homo sapiens ] | Official Symbol : CD80 | Synonyms : CD80; CD80 molecule; CD28LG, CD28LG1, CD80 antigen (CD28 antigen ligand 1, B7 1 antigen) , CD80 molecule; T-lymphocyte activation antigen CD80; B lymphocyte activation antigen B7; B7 1; B7.1; activation B7-1 antigen; costimulatory factor CD80; CTLA-4 counter-receptor B7.1; B-lymphocyte activation antigen B7; costimulatory molecule variant IgV-CD80; CD80 antigen (CD28 antigen ligand 1, B7-1 antigen); B7; BB1; B7-1; LAB7; CD28LG; CD28LG1; | Gene ID : 941 | mRNA Refseq : NM_005191 | Protein Refseq : NP_005182 | MIM : 112203 | UniProt ID : P33681 | Chromosome Location : 3q13.3-q21 | Pathway : Adaptive Immune System, organism-specific biosystem; Allograft rejection, organism-specific biosystem; Allograft rejection, conserved biosystem; Autoimmune thyroid disease, organism-specific biosystem; Autoimmune thyroid disease, conserved biosystem; CD28 co-stimulation, organism-specific biosystem; CD28 dependent PI3K/Akt signaling, organism-specific biosystem; | Function : coreceptor activity; protein binding; receptor activity;

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Author: Cholesterol Absorption Inhibitors