Active Recombinant Human CLEC12A Protein (Thr67-Ala265), N-hFc tagged

Specification :
| Description : This gene encodes a member of the C-type lectin/C-type lectin-like domain (CTL/CTLD) superfamily. Members of this family share a common protein fold and have diverse functions, such as cell adhesion, cell-cell signaling, glycoprotein turnover, and roles in inflammation and immune response. The protein encoded by this gene is a negative regulator of granulocyte and monocyte function. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been determined. This gene is closely linked to other CTL/CTLD superfamily members in the natural killer gene complex region on chromosome 12p13. | Source : CHO | Species : Human | Tag : N-hFc | Form : Disulfide-linked homodimer | Bio-activity : Measured by its binding ability in a functional ELISA. When Recombinant Human Integrin alpha X beta 2 Protein is immobilized at 5.00 μg/mL, 100 μL/well, the concentration of Recombinant Human MICL/CLEC12A Fc Chimera that produces 50 % of the optimal binding response is approximately 1.20-12.0 μg/mL. | Molecular Mass : Predicted Molecular Mass: 50 kDaSDS-PAGE: 70-85 kDa, under reducing conditions | Protein Length : Thr67-Ala265 | N-terminal Sequence Analysis : Met | Endotoxin : | Purity : > 90 %, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie Blue Staining. | Storage : Use a manual defrost freezer and avoid repeated freeze-thaw cycles.12 months from date of receipt, -20 to -70 centigrade as supplied.1 month, 2 to 8 centigrade under sterile conditions after reconstitution.3 months, -20 to -70 centigrade under sterile conditions after reconstitution. | Storage Buffer : Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. | Reconstitution : Reconstitute at 500 μg/mL in PBS. | Shipping : The product is shipped at ambient temperature.