Name :
Recombinant Human CD86 Protein, Fc-tagged
Specification :
| Description : This gene encodes a type I membrane protein that is a member of the immunoglobulin superfamily. This protein is expressed by antigen-presenting cells, and it is the ligand for two proteins at the cell surface of T cells, CD28 antigen and cytotoxic T-lymphocyte-associated protein 4. Binding of this protein with CD28 antigen is a costimulatory signal for activation of the T-cell. Binding of this protein with cytotoxic T-lymphocyte-associated protein 4 negatively regulates T-cell activation and diminishes the immune response. Alternative splicing results in several transcript variants encoding different isoforms. | Source : Human cells | Species : Human | Tag : Fc | Form : Purified protein formulated in a sterile solution of TBS buffer, pH7.396, without any preservatives. | Molecular Mass : 70 kDa | Protein length : Leu26-His245 | Endotoxin : Endotoxin level is | Purity : >90% by SDS-PAGE gel and Coomassie Blue staining | Applications : Antigens, Western, ELISA and other in vitro binding or in vivo functional assays, and protein-protein interaction studies.
Gene Information :
| Gene Name : CD86 CD86 molecule [ Homo sapiens ] | Official Symbol : CD86 | Synonyms : CD86; CD86 molecule; CD28LG2, CD86 antigen (CD28 antigen ligand 2, B7 2 antigen); T-lymphocyte activation antigen CD86; B lymphocyte antigen B7 2; B7 2; B7.2; BU63; FUN-1; CTLA-4 counter-receptor B7.2; B-lymphocyte activation antigen B7-2; CD86 antigen (CD28 antigen ligand 2, B7-2 antigen); B70; B7-2; LAB72; CD28LG2; MGC34413; | Gene ID : 942 | mRNA Refseq : NM_001206924 | Protein Refseq : NP_001193853 | MIM : 601020 | UniProt ID : P42081
Related category websites: https://www.medchemexpress.com/recombinant-proteins.html
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