Recombinant Human CD86 Protein, Fc-tagged

Specification :
| Description : This gene encodes a type I membrane protein that is a member of the immunoglobulin superfamily. This protein is expressed by antigen-presenting cells, and it is the ligand for two proteins at the cell surface of T cells, CD28 antigen and cytotoxic T-lymphocyte-associated protein 4. Binding of this protein with CD28 antigen is a costimulatory signal for activation of the T-cell. Binding of this protein with cytotoxic T-lymphocyte-associated protein 4 negatively regulates T-cell activation and diminishes the immune response. Alternative splicing results in several transcript variants encoding different isoforms. | Source : HEK293 | Species : Human | Tag : Fc | Form : Lyophilized | Molecular Mass : 51.5 kDa | Protein Length : 329 | AA Sequence : MDPQCTMGLSNILFVMAFLLSGAAP LKIQAYFNETADLPCQFANSQNQSL SELVVFWQDQENLVLNEVYLGKEKF DSVHSKYMGRTSFDSDSWTLRLHNL QIKDKGLYQCIIHHKKPTGMIRIHQ MNSELSVLANFSQPEIVPISNITEN VYINLTCSSIHGYPEPKKMSVLLRT KNSTIEYDGVMQKSQDNVTELYDVS ISLSVSFPDVTSNMTIFCILETDKT RLLSSPFSIELEDPQPPPDHIPWIT AVLPTVIICVMVFCLILWKWKKKKR PRNSYKCGTNTMEREESEQTKKREK IHIPERSDEAQRVFKSSKTSSCDKS DTCF | Purity : > 98% | Applications : WB; ELISA; FACS; FC | Stability : This bioreagent is stable at 4 centigrade (short-term) and -70 centigrade(long-term). After reconstitution, sample may be stored at 4 centigrade for 2-7 days and below -18 centigrade for future use. | Storage : At -20 centigrade. | Concentration : 1 mg/mL | Storage Buffer : PBS (pH 7.4-7.5). Sterile-filtered colorless solution. | Reconstitution : Reconstitute in sterile distilled H2O to no less than 100 μg/mL; dilute reconstituted stock further in other aqueous solutions if needed. Please review COA for lot-specific instructions. Final measurements should be determined by the end-user for optimal performance.