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Name :
Recombinant Human CD86 protein, His-Avi-tagged

Specification :
| Description : Human B7-H2, also called B7RP-1, B7h, LICOS, and GL50, is a member of the growing B7 family of immune costimulatory proteins. Other family members include B7-1, B7-2, B7-H1(PD-L1), PD-L2, and B7-H3. B7 proteins are members of the immunoglobulin(Ig) superfamily, the extracellular domains contain 2 Ig-like domains and all members have short cytoplasmic domains. Among the family members, they share about 20-25% amino acid identity. Human and mouse B7-H2 share approximately 49% amino acid identity. | Source : HEK293 | Species : Human | Tag : His-Avi | Form : Supplied as 0.22μm filtered solution in PBS (pH 7.4). | Molecular Mass : The protein has a predicted MW of 28.2 kDa. Due to glycosylation, the protein migrates to 55-70 kDa based on Bis-Tris PAGE result. | Protein length : Leu26-Pro247 | Endotoxin : Less than 0.05 EU per μg by the LAL method. | Purity : >95% as determined by Bis-Tris PAGE; >95% as determined by HPLC | Storage : The product should be stored at -70°C. Please do not repeated freeze-thaw cycles.

Gene Information :
| Gene Name : CD86 | Official Symbol : CD86 | Synonyms : CD86 antigen; CD86 molecule; CD86; B70; B7-2 antigen; B72; B7-2; Activation B7-2 antigen; B-lymphocyte activation antigen B7-2; BU63; CD28 antigen ligand 2; CD28LG2B7-2 antigen); CTLA-4 counter-receptor B7.2; FUN-1; LAB72; MGC34413; T-lymphocyte activation antigen CD86 | Gene ID : 942 | mRNA Refseq : NM_001206924.1 | Protein Refseq : NP_001193853.1 | MIM : 601020 | UniProt ID : P42081

MedChemExpress (MCE) recombinant proteins include: cytokines, enzymes, growth factors, hormones, receptors, transcription factors, antibody fragments, etc. They are often essential for supporting cell growth, stimulating cell signaling pathways, triggering or inhibiting cell differentiation; and are useful tools for elucidating protein structure and function, understanding disease onset and progression, and validating pharmaceutical targets. At MedChemExpress (MCE), we strive to provide products with only the highest quality. Protein identity, purity and biological activity are assured by our robust quality control and assurance procedures.
Related category websites: https://www.medchemexpress.com/recombinant-proteins.html
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Author: Cholesterol Absorption Inhibitors