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Name :
Active Recombinant Human CD86 Protein, His & Avi-tagged, Biotinylated

Specification :
| Source : HEK293 | Species : Human | Tag : His & Avi | Predicted N Terminal : Leu 26 | Form : Lyophilized from sterile PBS, pH7.4, 10% trehalose. | Bio-activity : Immobilized Human CTLA-4, Fc Tag at 10μg/mL (100 μL/well) can bind Biotinylated Human B7-2, His Tag with a linear range of 0.01-0.15 μg/mL. | Molecular Mass : Recombinant Human CD86 Protein has a calculated MW of 28 kDa. The protein migrates as 45-65 kDa on a SDS-PAGE gel under reducing (R) condition due to glycosylation. | Protein length : Leu 26 – Pro 247 | Endotoxin : Less than 1.0 EU per μg by the LAL method. | Purity : >90% as determined by SDS-PAGE. | Stability : Samples are stable for up to twelve months from date of receipt at -70ºC. | Storage : Store it under sterile conditions at -20ºC~-70ºC. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles. | Reconstitution : It is recommended that sterile water be added to the vial to prepare a stock solution of 0.2 ug/ul. Centrifuge the vial at 4℃ before opening to recover the entire contents.

Gene Information :
| Gene Name : CD86 CD86 molecule [ Homo sapiens ] | Official Symbol : CD86 | Synonyms : CD86; CD86 molecule; CD28LG2, CD86 antigen (CD28 antigen ligand 2, B7 2 antigen); T-lymphocyte activation antigen CD86; B lymphocyte antigen B7 2; B7 2; B7.2; BU63; FUN-1; CTLA-4 counter-receptor B7.2; B-lymphocyte activation antigen B7-2; CD86 antigen (CD28 antigen ligand 2, B7-2 antigen); B70; B7-2; LAB72; CD28LG2; MGC34413; | Gene ID : 942 | mRNA Refseq : NM_001206924 | Protein Refseq : NP_001193853 | MIM : 601020 | UniProt ID : P42081 | Chromosome Location : 3q21 | Pathway : Adaptive Immune System, organism-specific biosystem; Allograft rejection, organism-specific biosystem; Allograft rejection, conserved biosystem; Autoimmune thyroid disease, organism-specific biosystem; Autoimmune thyroid disease, conserved biosystem; CD28 co-stimulation, organism-specific biosystem; CD28 dependent PI3K/Akt signaling, organism-specific biosystem; | Function : coreceptor activity; protein binding; receptor activity;

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Author: Cholesterol Absorption Inhibitors