Recombinant Human CD86 Protein, His-Flag-StrepII-Tagged

Specification :
| Description : This gene encodes a type I membrane protein that is a member of the immunoglobulin superfamily. This protein is expressed by antigen-presenting cells, and it is the ligand for two proteins at the cell surface of T cells, CD28 antigen and cytotoxic T-lymphocyte-associated protein 4. Binding of this protein with CD28 antigen is a costimulatory signal for activation of the T-cell. Binding of this protein with cytotoxic T-lymphocyte-associated protein 4 negatively regulates T-cell activation and diminishes the immune response. Alternative splicing results in several transcript variants encoding different isoforms.[provided by RefSeq, May 2011] | Source : Human cells | Species : Human | Tag : His-Flag-StrepII | Form : Liquid | Bio-activity : Not Tested | Molecular Mass : 29.81 kDa | AA Sequence : APLKIQAYFNETADLPCQFANSQNQ SLSELVVFWQDQENLVLNEVYLGKE KFDSVHSKYMGRTSFDSDSWTLRLH NLQIKDKGLYQCIIHHKKPTGMIRI HQMNSELSVLANFSQPEIVPISNIT ENVYINLTCSSIHGYPEPKKMSVLL RTKNSTIEYDGIMQKSQDNVTELYD VSISLSVSFPDVTSNMTIFCILETD KTRLLSSPFSIELEDPQPPPDHI | Applications : Western BlotEnzyme-linked Immunoabsorbent AssaySDS-PAGEProtein Interaction | Storage : Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing. | Concentration : ≥ 10 μg/mL | Storage Buffer : 100 mM Tris-HCl pH 8.0, 150 mM NaCl, 1 mM EDTA, and 5 mM desthiobiotin.