Recombinant Human CDH1 Protein, C-8His tagged, Biotinylated

Specification :
| Description : E-Cadherin is a calcium-dependent cell adhesion glycoprotein that belongs to the cadherin family. E-Cadherin is expressed in non-neural epithelial tissues. It tends to interact with each other in a homophilic manner in connecting cells. E-Cadherin clusters are critical components of adherent junctions between epithelial cells and act in the formation and maintenance of the epithelial cell barrier. E-Cadherin is involved in mechanisms regulating cell-cell adhesions, mobility and proliferation of epithelial cells and has a potent invasive suppressor role. E-Cadherin loss contributes to cancer metastasis. The extracellular E-Cadherin N-terminal domain can be cleaved by several proteases and is released as a soluble factor that enhances cancer cell motility and EGFR-dependent survival and proliferation. | Source : HEK293 | Species : Human | Tag : C-8His | Protein Length : Q23-A709 | Storage Buffer : Lyophilized from a 0.2 μm filtered solution of PBS, pH7.2 | Shipping : Ambient