Name :
Recombinant Human CDK1/CyclinB1, GST-tagged, Active
Specification :
| Source : Insect cells | Species : Human | Tag : GST | Form : 50mM Tris-HCl, pH 7.5, 150mM NaCl, 10mM glutathione, 0.1mM EDTA, 0.25mM DTT, 0.1mM PMSF, 25% glycerol. | Molecular Mass : ~58 kDa and CyclinB1 ~75 kDa | Purity : > 75% | Applications : Kinase Assay, Western Blot | Stability : 1 year at –70 centigrade from date of shipment | Storage : Store product at –70 centigrade. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles. | Concentration : 0.1 ug/ul
Gene Information :
| Gene Name : CDK1 cyclin-dependent kinase 1 [ Homo sapiens ] | Official Symbol : CDK1 | Synonyms : CDK1; cyclin-dependent kinase 1; CDC2, cell division cycle 2, G1 to S and G2 to M; CDC28A; p34 protein kinase; cell cycle controller CDC2; cell division protein kinase 1; cell division control protein 2 homolog; cell division cycle 2, G1 to S and G2 to M; CDC2; P34 centigradeDC2; MGC111195; DKFZp686L20222; | Gene ID : 983 | mRNA Refseq : NM_001786 | Protein Refseq : NP_001777 | MIM : 116940 | UniProt ID : P06493 | Chromosome Location : 10q21.2 | Pathway : APC/C-mediated degradation of cell cycle proteins, organism-specific biosystem; APC/C:Cdc20 mediated degradation of Cyclin B, organism-specific biosystem; APC/C:Cdc20 mediated degradation of mitotic proteins, organism-specific biosystem; ARMS-mediated activation, organism-specific biosystem; Activated TLR4 signalling, organism-specific biosystem; Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins, organism-specific biosystem; Androgen Receptor Signaling Pathway, organism-specific biosystem; | Function : ATP binding; Hsp70 protein binding; RNA polymerase II carboxy-terminal domain kinase activity; cyclin binding; cyclin-dependent protein kinase activity; cyclin-dependent protein kinase activity; histone kinase activity; nucleotide binding; protein binding
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