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Name :
Recombinant Human CDK7 Protein, GST-Tagged

Specification :
| Description : The protein encoded by this gene is a member of the cyclin-dependent protein kinase (CDK) family. CDK family members are highly similar to the gene products of Saccharomyces cerevisiae cdc28, and Schizosaccharomyces pombe cdc2, and are known to be important regulators of cell cycle progression. This protein forms a trimeric complex with cyclin H and MAT1, which functions as a Cdk-activating kinase (CAK). It is an essential component of the transcription factor TFIIH, that is involved in transcription initiation and DNA repair. This protein is thought to serve as a direct link between the regulation of transcription and the cell cycle. [provided by RefSeq, Jul 2008] | Source : Wheat Germ | Species : Human | Tag : GST | Molecular Mass : 63.58 kDa | AA Sequence : MALDVKSRAKRYEKLDFLGEGQFAT VYKARDKNTNQIVAIKKIKLGHRSE AKDGINRTALREIKLLQELSHPNII GLLDAFGHKSNISLVFDFMETDLEV IIKDNSLVLTPSHIKAYMLMTLQGL EYLHQHWILHRDLKPNNLLLDENGV LKLADFGLAKSFGSPNRAYTHQVVT RWYRAPELLFGARMYGVGVDMWAVG CILAELLLRVPFLPGDSDLDQLTRI FETLGTPTEEQWPDMCSLPDYVTFK SFPGIPLHHIFSAAGDDLLDLIQGL FLFNPCARITATQALKMKYFSNRPG PTPGCQLPRPNCPVETLKEQSNPAL AIKRKRTEALEQGGLPKKLIF | Applications : Enzyme-linked Immunoabsorbent AssayWestern Blot (Recombinant protein)Antibody ProductionProtein Array | Storage : Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing. | Storage Buffer : 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information :
| Gene Name : CDK7 cyclin-dependent kinase 7 [ Homo sapiens ] | Official Symbol : CDK7 | Synonyms : CDK7; cyclin-dependent kinase 7; cyclin dependent kinase 7 (homolog of Xenopus MO15 cdk activating kinase), cyclin dependent kinase 7 (MO15 homolog, Xenopus laevis, cdk activating kinase); CAK; CAK1; CDKN7; MO15; STK1; p39 Mo15; protein kinase; 39 KDa protein kinase; kinase subunit of CAK; CDK-activating kinase 1; serine/threonine kinase stk1; cell division protein kinase 7; serine/threonine protein kinase 1; serine/threonine-protein kinase 1; serine/threonine protein kinase MO15; homolog of Xenopus MO15 Cdk-activating kinase; TFIIH basal transcription factor complex kinase subunit; cyclin-dependent kinase 7 (MO15 homolog, Xenopus laevis, cdk-activating kinase); HCAK; p39MO15; | Gene ID : 1022 | mRNA Refseq : NM_001799 | Protein Refseq : NP_001790 | MIM : 601955 | UniProt ID : P50613

MedChemExpress (MCE) recombinant proteins include: cytokines, enzymes, growth factors, hormones, receptors, transcription factors, antibody fragments, etc. They are often essential for supporting cell growth, stimulating cell signaling pathways, triggering or inhibiting cell differentiation; and are useful tools for elucidating protein structure and function, understanding disease onset and progression, and validating pharmaceutical targets. At MedChemExpress (MCE), we strive to provide products with only the highest quality. Protein identity, purity and biological activity are assured by our robust quality control and assurance procedures.
Related category websites: https://www.medchemexpress.com/recombinant-proteins.html
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Author: Cholesterol Absorption Inhibitors