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Name :
Active Recombinant Human CTLA4 protein, mFc-Avi-tagged, Biotinylated

Specification :
| Source : HEK293 | Species : Human | Tag : mFc-Avi | Form : Lyophilized from 0.22 μm filtered solution in 50 mM Tris, 100 mM Glycine, 25 mM Arginine, 150 mM NaCl, pH7.5. Normally trehalose is added as protectant before lyophilization. | Bio-activity : Immobilized Human B7-1, Fc Tag (HPLC-verified) at 5 μg/mL (100 μL/well) can bind Biotinylated Humane CTLA-4, Mouse IgG2a Fc,Avitag with a linear range of 0.3-5 ng/mL.Immobilized Human B7-2, Fc Tag at 5 μg/mL (100 μL/well) can bind Biotinylated Humane CTLA-4, Mouse IgG2a Fc,Avitag with a linear range of 0.3-2 ng/mL.Immobilized Ipilimumab at 5 μg/mL (100 μL/well) can bind Biotinylated Humane CTLA-4, Mouse IgG2a Fc,Avitag with a linear range of 0.2-2 ng/mL. | Molecular Mass : This protein carries a mouse IgG2a Fc tag at the C-terminus, followed by an Avi tag (Avitag™).The protein has a calculated MW of 42.1 kDa. The protein migrates as 50-55 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation. | Proteinlength : Ala37-Phe162 | Endotoxin : Less than 1.0 EU per μg by the LAL method. | Purity : >95% as determined by SDS-PAGE. | Storage : For long term, the product should be stored at lyophilized state at -20°C or lower.Please avoid repeated freeze-thaw cycles. This product is stable after at: -20°C to -70°C for 12 months in lyophilized state; -70°C for 3 months under sterile conditions after reconstitution. | Reconstitution : It is recommended that sterile water be added to the vial to prepare a stock solution of 0.2 ug/ul. Centrifuge the vial at 4°C before opening to recover the entire contents.

Gene Information :
| Gene Name : CTLA4 cytotoxic T-lymphocyte-associated protein 4 [ Homo sapiens ] | Official Symbol : CTLA4 | Synonyms : CTLA4; cytotoxic T-lymphocyte-associated protein 4; celiac disease 3 , CELIAC3; cytotoxic T-lymphocyte protein 4; CD; CD28; CD152; GSE; ICOS; CD152 isoform; celiac disease 3; cytotoxic T-lymphocyte antigen 4; cytotoxic T-lymphocyte-associated antigen 4; cytotoxic T-lymphocyte-associated serine esterase-4; cytotoxic T lymphocyte associated antigen 4 short spliced form; ligand and transmembrane spliced cytotoxic T lymphocyte associated antigen 4; GRD4; CTLA-4; IDDM12; CELIAC3; | Gene ID : 1493 | mRNA Refseq : NM_001037631 | Protein Refseq : NP_001032720 | UniProt ID : P16410

MedChemExpress (MCE) recombinant proteins include: cytokines, enzymes, growth factors, hormones, receptors, transcription factors, antibody fragments, etc. They are often essential for supporting cell growth, stimulating cell signaling pathways, triggering or inhibiting cell differentiation; and are useful tools for elucidating protein structure and function, understanding disease onset and progression, and validating pharmaceutical targets. At MedChemExpress (MCE), we strive to provide products with only the highest quality. Protein identity, purity and biological activity are assured by our robust quality control and assurance procedures.
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Author: Cholesterol Absorption Inhibitors