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Name :
Recombinant Human CLEC4C Protein, His-tagged

Specification :
| Description : Lectin-type cell surface receptor which may play a role in antigen capturing by dendritic cells. Specifically recognizes non-sialylated galactose-terminated biantennary glycans containing the trisaccharide epitope Gal(beta1-3/4)GlcNAc(beta1-2)Man. Binds to serum IgG. Efficiently targets ligand into antigen-processing and peptide-loading compartments for presentation to T-cells. May mediate potent inhibition of induction of IFN-alpha/beta expression in plasmacytoid dendritic cells. May act as a signaling receptor that activates protein-tyrosine kinases and mobilizes intracellular calcium. | Source : E. coli | Species : Human | Tag : His | Molecular Mass : ~23 kDa | AA Sequence : NFMYSKTVKRLSKLREYQQYHPSLT CVMEGKDIEDWSCCPTPWTSFQSSC YFISTGMQSWTKSQKNCSVMGADLV VINTREEQDFIIQNLKRNSSYFLGL SDPGGRRHWQWVDQTPYNENVTFWH SGEPNNLDERCAIINFRSSEEWGWN DIHCHVPQKSICKMKKIYI | Purity : Transferred into competent cells and the supernatant was purified by NI column affinity chromatography and the purity is > 85% (by SDS-PAGE). | Notes : For research use only, not for use in diagnostic procedure. | Storage : Store at 4 centigrade short term. Aliquot and store at -20 centigrade long term. Avoid freeze-thaw cycles. | Storage Buffer : PBS, 4M Urea, pH7.4

Gene Information :
| Gene Name : CLEC4C C-type lectin domain family 4, member C [ Homo sapiens (human) ] | Official Symbol : CLEC4C | Synonyms : DLEC; HECL; BDCA2; CD303; CLECSF7; CLECSF11; PRO34150 | Gene ID : 170482 | mRNA Refseq : NM_203503 | Protein Refseq : NP_987099 | MIM : 606677 | UniProt ID : Q8WTT0

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Author: Cholesterol Absorption Inhibitors