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Name :
Recombinant Human CRKL Protein, GST-tagged

Specification :
| Description : This gene encodes a protein kinase containing SH2 and SH3 (src homology) domains which has been shown to activate the RAS and JUN kinase signaling pathways and transform fibroblasts in a RAS-dependent fashion. It is a substrate of the BCR-ABL tyrosine kinase, plays a role in fibroblast transformation by BCR-ABL, and may be oncogenic.[provided by RefSeq, Jan 2009] | Source : Wheat Germ | Species : Human | Tag : GST | Molecular Mass : 60.2 kDa | AA Sequence : MSSARFDSSDRSAWYMGPVSRQEAQ TRLQGQRHGMFLVRDSSTCPGDYVL SVSENSRVSHYIINSLPNRRFKIGD QEFDHLPALLEFYKIHYLDTTTLIE PAPRYPSPPMGSVSAPNLPTAEDNL EYVRTLYDFPGNDAEDLPFKKGEIL VIIEKPEEQWWSARNKDGRVGMIPV PYVEKLVRSSPHGKHGNRNSNSYGI PEPAHAYAQPQTTTPLPAVSGSPGA AITPLPSTQNGPVFAKAIQKRVPCA YDKTALALEVGDIVKVTRMNINGQW EGEVNGRKGLFPFTHVKIFDPQNPD ENE | Applications : Enzyme-linked Immunoabsorbent AssayWestern Blot (Recombinant protein)Antibody ProductionProtein Array | Notes : Best use within three months from the date of receipt of this protein. | Storage : Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing. | Storage Buffer : 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information :
| Gene Name : CRKL CRK like proto-oncogene, adaptor protein [ Homo sapiens (human) ] | Official Symbol : CRKL | Synonyms : CRKL; CRK like proto-oncogene, adaptor protein; v-crk sarcoma virus CT10 oncogene homolog (avian)-like; v crk avian sarcoma virus CT10 oncogene homolog like; crk-like protein; | Gene ID : 1399 | mRNA Refseq : NM_005207 | Protein Refseq : NP_005198 | MIM : 602007 | UniProt ID : P46109

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Author: Cholesterol Absorption Inhibitors