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Name :
Recombinant Human CSF1R, GST-tagged, Active

Specification :
| Cat. No. : CSF1R-320H | Description : FMS is a proto-oncogene that encodes the tyrosine kinase transmembrane receptor for colony stimulating factor 1 (CSF1). FMS is homodimeric that contains a so-called kinase insert domain and is a member of the CSF1/PDGF receptor family of tyrosine-protein kinases. FMS mediates most if not all of the biological effects of CSF1 which control the production, differentiation, and function of cell of the monocyte/macrophage lineage. Mutations in FMS have been associated with providing sustained signals for cell growth and a predisposition to myeloid malignancy. | Source : Sf9 insect cells using baculovirus. | Sequence : 593-end. | Applications : Kinase Assay, Western Blot. | Storage And Stability : Store product at –70°C. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.

Gene Information :
| Gene Name : CSF1R colony stimulating factor 1 receptor [ Homo sapiens ] | Synonyms : CSF1R; colony stimulating factor 1 receptor; C-FMS; CD115; CSFR; FIM2; FMS; CD115 antigen; FMS proto-oncogene; McDonough feline sarcoma viral (v-fms) oncogene homolog; macrophage colony stimulating factor I receptor; EC 2.7.10.1; soluble CSF1R variant 1 | Gene ID : 1436 | mRNA Refseq : NM_005211 | Protein Refseq : NP_005202 | UniProt ID : P07333 | Chromosome Location : 5q33-q35 | MIM : 164770 | Pathway : Cytokine-cytokine receptor interaction; Hematopoietic cell lineage; Endocytosis; Pathways in cancer | Function : ATP binding; cytokine binding; macrophage colony stimulating factor receptor activity; nucleotide binding; protein homodimerization activity; receptor activity; transferase activity

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Author: Cholesterol Absorption Inhibitors