Product: BM25518-Hydroxy-Guanosine / 8-OHG antibody
Quantity: 0.1 mg
Synonyms: 8-Hydroxy-2-deoxyguanosine, 8-Hydroxyguanine, 8-Hydroxyguanosine, 8-OFdG, 8-OHG, 8OG, 8OHG, 8OHdG
Presentation: Purified
Clonality: Monoclonal
Host: Mouse
Isotype: IgG2b
CAS NO: 875051-72-2 Product: PF-01247324
Shipping to: Worldwide
Immunogen: 8-Hydroxyguanosine (OH8G)-BSA and -casein conjugates.
Application: Suitable for use in ELISA and Immunohistochemistry (PLP-Fixed Sections) to detect the markers of oxidative damage to DNA and RNA.May also be used on Immunoaffinity columns to isolate oxidative DNA damage adducts from biological fluids.
Background: 8 Hydroxyguanosine (80G) is a modified base which occurs in DNA as a result of oxidative stress. 8 Hydroxy-2deoxyguanosine (8OHdG) has become a sensitive marker of oxidative damage in cellular DNA and has been reported to be excreted in the urine. Levels
Concentration: 1.0 mg/ml (OD 280 nm)
Storage: Store the antibody undiluted at 2-8°C.DO NOT FREEZE!Shelf life: one year from despatch.
Buffer System: TBS, pH 7.4 with 0.09% Sodium Azide as preservative.
Preservatives:
State: Liquid purified Ig fraction.Purified
Specifictiy: This antibody recognizes 8-hydroxy-2-deoxyguanosine (OH8dG), 8-hydroxyguanine (OH8G), and 8-hydroxyguanosine (OH8G).These are markers of oxidative damage to DNA and RNA.
