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Name :
Recombinant Human CSF2RA protein, His-Avi-tagged, Biotinylated

Specification :
| Description : CSF2R, also known as CD116, is a component of the receptor complex that mediates cellular responses to GM-CSF. GM-CSF promotes the differentiation and mobilization of granulocytemacrophage, erythroid, megakaryocyte, and eosinophil progenitors. CSF2R is a low affinity receptor for granulocyte-macrophage colony-stimulating factor. Transduces a signal that results in the proliferation, differentiation, and functional activation of hematopoietic cells. | Source : HEK293 | Species : Human | Tag : His-Avi | Form : Supplied as 0.22μm filtered solution in 20mM PBS,pH7.4. | Molecular Mass : The protein has a predicted MW of 37.7 KDa. Due to glycosylation, the protein migrates to 68-75 KDa based on Bis-Tris PAGE result. | Protein length : Glu23-Gly320 | Endotoxin : Less than 0.05 EU per μg by the LAL method. | Purity : >95% as determined by Tris-Bis PAGE; >95% as determined by HPLC | Storage : The product should be stored at -70°C. Please do not repeated freeze-thaw cycles.

Gene Information :
| Gene Name : CSF2RA | Official Symbol : CSF2RA | Synonyms : CD116 antigen; CD116; CDw116; colony stimulating factor 2 receptor alpha subunit; colony stimulating factor 2 receptor, alpha, low-affinity(granulocyte-macrophage); CSF2R; CSF2RA; CSF2RAX; CSF2RAY; CSF2RX; CSF2RY; GM-CSF R alpha; GM-CSF receptor alpha subunit; GMCSFR alpha; GMCSFR; GM-CSFRa; GM-CSF-R-alpha; GMCSFR-alpha; GMR; GMR-alpha; granulocyte-macrophage colony-stimulating factor receptor alpha chain; granulocyte-macrophage colony-stimulating factor receptor subunit alpha; MGC3848; MGC4838 | Gene ID : 1438 | mRNA Refseq : NM_001161529.2 | Protein Refseq : NP_001155001.1 | MIM : 425000 | UniProt ID : P15509

MedChemExpress (MCE) recombinant proteins include: cytokines, enzymes, growth factors, hormones, receptors, transcription factors, antibody fragments, etc. They are often essential for supporting cell growth, stimulating cell signaling pathways, triggering or inhibiting cell differentiation; and are useful tools for elucidating protein structure and function, understanding disease onset and progression, and validating pharmaceutical targets. At MedChemExpress (MCE), we strive to provide products with only the highest quality. Protein identity, purity and biological activity are assured by our robust quality control and assurance procedures.
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Author: Cholesterol Absorption Inhibitors