Name :
Active Recombinant Human DPP4, His tagged
Specification :
| Description : The protein encoded by this gene is identical to adenosine deaminase complexing protein-2, and to the T-cell activation antigen CD26. It is an intrinsic membrane glycoprotein and a serine exopeptidase that cleaves X-proline dipeptides from the N-terminus of polypeptides. | Source : High-5 cells | Species : Human | Tag : His | Form : DPP4 is formulated in 20 mM Tris-HCl buffer pH-8, 100mM NaCl, 1mM EDTA and 10% glycerol. | Bio-activity : >20 Units/mg. | AA Sequence : ADP-SRKTYTLTDYLKNTYRLKLYSLRWI SDHEYLYKQENNILVFNAEYGNSSV FLENSTFDEFGHSINDYSISP DGQFILLEYNYVKQWRHSYTASYDI YDLNKRQLITEERIPNNTQWVTWSP VGHKLAYVWNNDIYVKIEPNLPSYR ITWTGKEDIIYNGITDWVYEEEVFS AYSALWWSPNGTFLAYAQFNDTEVP LIEYSFYSDESLQYPKTVRVPYPKA GAVNPTVKFFVVNTDSLSSVTNATS IQITAPASMLIGDHYLCDVTWATQE RISLQWLRRIQNYSVMDICDYDESS GRWNCLVARQHIEMSTTGWVGRFRP SEPHFTLDGNSFYKIISNEEGYRHI CYFQIDKKDCTFITKGTWEVIGIEA LTSDYLYYISNEYKGMPGGRNLYKI QLSDYTKVTCLSCELNPERCQYYSV SFSKEAKYYQLRCSGPGLPLYTLHS SVNDKGLRVLEDNSALDKMLQNVQM PSKKLDFIILNETKFWYQMILPPHF DKSKKYPLLLDVYAGPCSQKADTVF RLNWATYLASTENIIVASFDGRGSG YQGDKIMHAINRRLGTFEVEDQIEA ARQFSKMGFVDNKRIAIWGWSYGGY VTSMVLGSGSGVFKCGIAVAPVSRW EYYDSVYTERYMGLPTPEDNLDHYR NSTVMSRAENFKQVEYLLIHGTADD NVHFQQSAQISKALVDVGVDFQAMW YTDEDHGIASSTAHQHIYTHMSHFI KQCFSLP-SGRLVPRGSHHHHHH. | Purity : Greater than 95.0% as determined by Analysis by SDS-PAGE.On SDS-PAGE under denatured condition, apparent molecular weight of glycosylated DPP4 will migrate at approximately 90kDa. | Applications : Unit Definition One unit will hydrolyze mmole of p-nitroaniline per minute at pH8.0 at 37℃ using 1mM of Gly-Pro p-nitroanilde as substrate. | Notes : For research use only. | Storage : DPP4 although stable 4 ℃ for weeks, should be stored desiccated below -18 ℃. For long term storage it is recommended to add carrier protein (0. 1% HSA or BSA). Please prevent freeze/thaw cycles.
Gene Information :
| Gene Name : DPP4 dipeptidyl-peptidase 4 [ Homo sapiens ] | Official Symbol : DPP4 | Synonyms : DPP4; dipeptidyl-peptidase 4; ADCP2, adenosine deaminase complexing protein 2 , CD26, dipeptidylpeptidase IV (CD26, adenosine deaminase complexing protein 2); dipeptidyl peptidase 4; DPPIV; ADCP-2; DPP IV; dipeptidylpeptidase 4; dipeptidyl peptidase IV; T-cell activation antigen CD26; adenosine deaminase complexing protein 2; dipeptidylpeptidase IV (CD26, adenosine deaminase complexing protein 2); CD26; ADABP; ADCP2; TP103; | Gene ID : 1803 | mRNA Refseq : NM_001935 | Protein Refseq : NP_001926 | MIM : 102720 | UniProt ID : P27487 | Chromosome Location : 2q23-qter | Pathway : Incretin Synthesis, Secretion, and Inactivation, organism-specific biosystem; Integration of energy metabolism, organism-specific biosystem; Metabolism, organism-specific biosystem; Protein digestion and absorption, organism-specific biosystem; Protein digestion and absorption, conserved biosystem; Regulation of Insulin Secretion, organism-specific biosystem; Synthesis, Secretion, and Inactivation of Glucagon-like Peptide-1 (GLP-1), organism-specific biosystem; | Function : aminopeptidase activity; collagen binding; dipeptidyl-peptidase activity; peptidase activity; peptide binding; protease binding; protein binding; protein homodimerization activity; receptor activity; receptor binding; serine-type endopeptidase activity; serine-type peptidase activity;
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