Name :
Recombinant Human CSF2RB Protein, C-His-tagged
Specification :
| Description : The common beta-chain (beta-c) of the granulocyte macrophage colony-stimulating factor (GM-CSF), interleukin-3 (IL-3) and IL-5 receptors is the major signaling subunit of these receptors, coupling ligand binding to multiple biological activities. Tyrosine phosphorylation of cytokine receptor common beta-chain is one of the first events in GM-CSF, IL-3 and IL-5 receptor activation and in signaling initiation. Serine phosphorylation within the 14-3-3 binding sequence of the common beta-chain is also involved in GM-CSF, IL-3 and IL-5 receptor-specific functions. | Source : E. coli | Species : Human | Tag : C-His | Molecular Mass : ~47 kDa | AA Sequence : WERSLAGAEETIPLQTLRCYNDYTS HITCRWADTQDAQRLVNVTLIRRVN EDLLEPVSCDLSDDMPWSACPHPRC VPRRCVIPCQSFVVTDVDYFSFQPD RPLGTRLTVTLTQHVQPPEPRDLQI STDQDHFLLTWSVALGSPQSHWLSP GDLEFEVVYKRLQDSWEDAAILLSN TSQATLGPEHLMPSSTYVARVRTRL APGSRLSGRPSKWSPEVCWDSQPGD EAQPQNLECFFDGAAVLSCSWEVRK EVASSVSFGLFYKPSPDAGEEECSP VLREGLGSLHTRHHCQIPVPDPATH GQYIVSVQPRRAEKHIKSSVNIQMA PPSLNVTKDGDSYSLRWETMKMRYE HIDHTFEIQYRKDTATWKDSKTETL QNAHSMALPALEPSTRYWARVRVRT SRTGYNGIWSEWSEARSWDTESVLP MW | Purity : Transferred into competent cells and the supernatant was purified by NI column affinity chromatography and the purity is > 85% (by SDS-PAGE). | Notes : For research use only, not for use in diagnostic procedure. | Storage : Store at 4 centigrade short term. Aliquot and store at -20 centigrade long term. Avoid freeze-thaw cycles. | Concentration : ≥0.5 mg/mL | Storage Buffer : PBS, 4M Urea, pH7.4
Gene Information :
| Gene Name : CSF2RB colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage) [ Homo sapiens (human) ] | Official Symbol : CSF2RB | Synonyms : CSF2RB; colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage); IL3RB; cytokine receptor common subunit beta; CD131; IL5RB; GM-CSF/IL-3/IL-5 receptor common beta-chain; GM-CSF/IL-3/IL-5 receptor common beta subunit; colony-stimulating factor-2 receptor, beta, low-affinity; interleukin 3 receptor/granulocyte-macrophage colony stimulating factor 3 receptor, beta (high affinity); SMDP5; CDw131; | Gene ID : 1439 | mRNA Refseq : NM_000395 | Protein Refseq : NP_000386 | MIM : 138981 | UniProt ID : P32927
Related category websites: https://www.medchemexpress.com/recombinant-proteins.html
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