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Name :
Active Recombinant Human CSNK1E Protein, GST-tagged

Specification :
| Description : The protein encoded by this gene is a serine/threonine protein kinase and a member of the casein kinase I protein family, whose members have been implicated in the control of cytoplasmic and nuclear processes, including DNA replication and repair. The encoded protein is found in the cytoplasm as a monomer and can phosphorylate a variety of proteins, including itself. This protein has been shown to phosphorylate period, a circadian rhythm protein. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Feb 2014] | Source : Insect Cells | Species : Human | Tag : GST | Form : Liquid | Bio-activity : The activity was measured by off-chip mobility shift assay. The enzyme was incubated with fluorescence-labeled substrate and Mg(or Mn)/ATP. The phosphorylated and unphosphorylated substrates were separated and detected by LabChip 3000. Substrate: CKtide. ATP: 100 uM. | Molecular Mass : 68 kDa | Purity : 54 % by SDS-PAGE/CBB staining | Applications : Functional StudySDS-PAGE | Storage : Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing. | Storage Buffer : In 50 mM Tris-HCl, 150 mM NaCl, pH 7.5 (0.1% CHAPS, 1 mM DTT, 10% glycerol)

Gene Information :
| Gene Name : CSNK1E casein kinase 1, epsilon [ Homo sapiens ] | Official Symbol : CSNK1E | Synonyms : CSNK1E; casein kinase 1, epsilon; casein kinase I isoform epsilon; CKIE; CKIepsilon; HCKIE; CKIe; CKI-epsilon; MGC10398; | Gene ID : 1454 | mRNA Refseq : NM_001894 | Protein Refseq : NP_001885 | MIM : 600863 | UniProt ID : P49674

MedChemExpress (MCE) recombinant proteins include: cytokines, enzymes, growth factors, hormones, receptors, transcription factors, antibody fragments, etc. They are often essential for supporting cell growth, stimulating cell signaling pathways, triggering or inhibiting cell differentiation; and are useful tools for elucidating protein structure and function, understanding disease onset and progression, and validating pharmaceutical targets. At MedChemExpress (MCE), we strive to provide products with only the highest quality. Protein identity, purity and biological activity are assured by our robust quality control and assurance procedures.
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Author: Cholesterol Absorption Inhibitors