Recombinant Human CTLA4 Protein, DDK/His-tagged

Specification :
| Description : This gene is a member of the immunoglobulin superfamily and encodes a protein which transmits an inhibitory signal to T cells. The protein contains a V domain, a transmembrane domain, and a cytoplasmic tail. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. The membrane-bound isoform functions as a homodimer interconnected by a disulfide bond, while the soluble isoform functions as a monomer. Mutations in this gene have been associated with insulin-dependent diabetes mellitus, Graves disease, Hashimoto thyroiditis, celiac disease, systemic lupus erythematosus, thyroid-associated orbitopathy, and other autoimmune diseases. | Source : HEK293 | Species : Human | Tag : DDK/His | Form : 1 x PBS, pH7.4, 10% glycerol | Molecular Mass : 16 kDa | Protein length : Ala37-Phe162 | Purity : > 80% as determined by SDS-PAGE and Coomassie blue staining | Concentration : >50 ug/mL as determined by microplate BCA method