Recombinant Human CTLA4 Protein, ECD, Tag Free, Biotinylated

Specification :
| Description : This gene is a member of the immunoglobulin superfamily and encodes a protein which transmits an inhibitory signal to T cells. The protein contains a V domain, a transmembrane domain, and a cytoplasmic tail. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. The membrane-bound isoform functions as a homodimer interconnected by a disulfide bond, while the soluble isoform functions as a monomer. Mutations in this gene have been associated with insulin-dependent diabetes mellitus, Graves disease, Hashimoto thyroiditis, celiac disease, systemic lupus erythematosus, thyroid-associated orbitopathy, and other autoimmune diseases. | Source : HEK293 | Species : Human | Tag : Tag Free | Protein length : ECD | Conjugation/Label : Biotin | Form : Lyophilised | Endotoxin : Endotoxin level was found to be less than 0.1 ng/μg (1 EU/μg). | Applications : ELISA, WB | Notes : FOR RESEARCH USE ONLY (RUO). | Storage : The lyophilized protein is stable for at least 1 year from date of receipt at -20 centigrade. Upon reconstitution, this cytokine can be stored in working aliquots at 2 to 8 centigrade for one month, or at -20 centigrade for six months, with a carrier protein without detectable loss | Storage Buffer : Lyophilised from 0.2 μm filtered PBS pH 7.4. | Reconstitution : Upon receipt a quick spin of the vial followed by reconstitution in distilled water to a concentration not less than 0.1 mg/mL. This solution can then be diluted into other buffers.