Recombinant Human CXCR3 protein, GST-tagged

Specification :
| Description : This gene encodes a G protein-coupled receptor with selectivity for three chemokines, termed CXCL9/Mig (monokine induced by interferon-g), CXCL10/IP10 (interferon-g-inducible 10 kDa protein) and CXCL11/I-TAC (interferon-inducible T cell a-chemoattractant). Binding of chemokines to this protein induces cellular responses that are involved in leukocyte traffic, most notably integrin activation, cytoskeletal changes and chemotactic migration. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. One of the isoforms (CXCR3-B) shows high affinity binding to chemokine, CXCL4/PF4 (PMID:12782716). | Source : Wheat Germ | Species : Human | Tag : GST | Form : 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer. | Molecular Mass : 67.1 kDa | AA Sequence : MVLEVSDHQVLNDAEVAALLENFSS SYDYGENESDSCCTSPPCPQDFSLN FDRAFLPALYSLLFLLGLLGNGAVA AVLLSRRTALSSTDTFLLHLAVADT LLVLTLPLWAVDAAVQWVFGSGLCK VAGALFNINFYAGALLLACISFDRY LNIVHATQLYRRGPPARVTLTCLAV WGLCLLFALPDFIFLSAHHDERLNA THCQYNFPQVGRTALRVLQLVAGFL LPLLVMAYCYAHILAVLLVSRGQRR LRAMRLVVVVVVAFALCWTPYHLVV LVDILMDLGALARNCGRESRVDVAK SVTSGLGYMHCCLNPLLYAFVGVKF RERMWMLLLRLGCPNQRGLQRQPSS SRRDSSWSETSEASYSGL | Applications : Enzyme-linked Immunoabsorbent Assay; Western Blot (Recombinant protein); Antibody Production; Protein Array | Notes : Best use within three months from the date of receipt of this protein. | Storage : Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.