Recombinant Human D2HGDH Protein, Myc/DDK-tagged, C13 and N15-labeled

Specification :
| Description : This gene encodes D-2hydroxyglutarate dehydrogenase, a mitochondrial enzyme belonging to the FAD-binding oxidoreductase/transferase type 4 family. This enzyme, which is most active in liver and kidney but also active in heart and brain, converts D-2-hydroxyglutarate to 2-ketoglutarate. Mutations in this gene are present in D-2-hydroxyglutaric aciduria, a rare recessive neurometabolic disorder causing developmental delay, epilepsy, hypotonia, and dysmorphic features. | Source : HEK293 | Species : Human | Tag : Myc/DDK | Molecular Mass : 56.4 kDa | AA Sequence : MLPRRPLAWPAWLLRGAPGAAGSWG RPVGPLARRGCCSAPGTPEVPLTRE RYPVQRLPFSTVSKQDLAAFERIVP GGVVTDPEALQAPNVDWLRTLRGCS KVLLRPRTSEEVSHILRHCHERNLA VNPQGGNTGMVGGSVPVFDEIILST ARMNRVLSFHSVSGILVCQAGCVLE ELSRYVEERDFIMPLDLGAKGSCHI GGNVATNAGGLRFLRYGSLHGTVLG LEVVLADGTVLDCLTSLRKDNTGYD LKQLFIGSEGTLGIITTVSILCPPK PRAVNVAFLGCPGFAEVLQTFSTCK GMLGEILSAFEFMDAVCMQLVGRHL HLASPVQESPFYVLIETSGSNAGHD AEKLGHFLEHALGSGLVTDGTMATD QRKVKMLWALRERITEALSRDGYVY KYDLSLPVERLYDIVTDLRARLGPH AKHVVGYGHLGDGNLHLNVTAEAFS PSLLAALEPHVYEWTAGQQGSVSAE HGVGFRKRDVLGYSKPPGALQLMQQ LKALLDPKGILNPYKTLPSQATRTR PLEQKLISEEDLAANDILDYKDDDD KV | Purity : > 80% as determined by SDS-PAGE and Coomassie blue staining | Stability : Stable for 3 months from receipt of products under proper storage and handling conditions. | Storage : Store at -80 centigrade. Avoid repeated freeze-thaw cycles. | Concentration : 50 μg/mL as determined by BCA | Storage Buffer : 100 mM glycine, 25 mM Tris-HCl, pH 7.3.