Recombinant Human DDR2 Protein (22-399aa), C-His tagged

Specification :
| Description : This gene encodes a member of the discoidin domain receptor subclass of the receptor tyrosine kinase (RTKs) protein family. RTKs play a key role in the communication of cells with their microenvironment. The encoded protein is a collagen-induced receptor that activates signal transduction pathways involved in cell adhesion, proliferation, and extracellular matrix remodeling. This protein is expressed in numerous cell types and may alos be involved in wound repair and regulate tumor growth and invasiveness. Mutations in this gene are the cause of short limb-hand type spondylometaepiphyseal dysplasia. | Source : Baculovirus | Species : Human | Tag : C-His | Form : Liquid | Molecular Mass : 43.7 kDa (386aa) | Protein Length : 22-399aa | AA Sequence : KAQVNPAICRYPLGMSGGQIPDEDI TASSQWSESTAAKYGRLDSEEGDGA WCPEIPVEPDDLKEFLQIDLHTLHF ITLVGTQGRHAGGHGIEFAPMYKIN YSRDGTRWISWRNRHGKQVLDGNSN PYDIFLKDLEPPIVARFVRFIPVTD HSMNVCMRVELYGCVWLDGLVSYNA PAGQQFVLPGGSIIYLNDSVYDGAV GYSMTEGLGQLTDGVSGLDDFTQTH EYHVWPGYDYVGWRNESATNGYIEI MFEFDRIRNFTTMKVHCNNMFAKGV KIFKEVQCYFRSEASEWEPNAISFP LVLDDVNPSARFVTVPLHHRMASAI KCQYHFADTWMMFSEITFQSDAAMY NNSEALPTSPMAPTTYDPMLKVDDS NTR | Endotoxin : | Purity : > 90% by SDS-PAGE | Applications : SDS-PAGE | Storage : Can be stored at +2 to +8 centigrade for 1 week. For long term storage, aliquot and store at -20 to -80 centigrade. Avoid repeated freezing and thawing cycles. | Concentration : 0.5 mg/mL (determined by absorbance at 280nm) | Storage Buffer : Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol