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Name :
Recombinant Human DGKA Protein, MYC/DDK-tagged, C13 and N15-labeled

Specification :
| Description : The protein encoded by this gene belongs to the eukaryotic diacylglycerol kinase family. It acts as a modulator that competes with protein kinase C for the second messenger diacylglycerol in intracellular signaling pathways. It also plays an important role in the resynthesis of phosphatidylinositols and phosphorylating diacylglycerol to phosphatidic acid. Several transcript variants encoding different isoforms have been identified for this gene. [provided by RefSeq, Apr 2017] | Source : HEK293 | Species : Human | Tag : Myc/DDK | Molecular Mass : 82.6 kDa | AA Sequence : MAKERGLISPSDFAQLQKYMEYSTK KVSDVLKLFEDGEMAKYVQGDAIGY EGFQQFLKIYLEVDNVPRHLSLALF QSFETGHCLNETNVTKDVVCLNDVS CYFSLLEGGRPEDKLEFTFKLYDTD RNGILDSSEVDKIILQMMRVAEYLD WDVSELRPILQEMMKEIDYDGSGSV SQAEWVRAGATTVPLLVLLGLEMTL KDDGQHMWRPKRFPRPVYCNLCESS IGLGKQGLSCNLCKYTVHDQCAMKA LPCEVSTYAKSRKDIGVQSHVWVRG GCESGRCDRCQKKIRIYHSLTGLHC VWCHLEIHDDCLQAVGHECDCGLLR DHILPPSSIYPSVLASGPDRKNSKT SQKTMDDLNLSTSEALRIDPVPNTH PLLVFVNPKSGGKQGQRVLWKFQYI LNPRQVFNLLKDGPEIGLRLFKDVP DSRILVCGGDGTVGWILETIDKANL PVLPPVAVLPLGTGNDLARCLRWGG GYEGQNLAKILKDLEMSKVVHMDRW SVEVIPQQTEEKSDPVPFQIINNYF SIGVDASIAHRFHIMREKYPEKFNS RMKNKLWYFEFATSESIFSTCKKLE ESLTVEICGKPLDLSNLSLEGIAVL NIPSMHGGSNLWGDTRRPHGDIYGI NQALGATAKVITDPDILKTCVPDLS DKRLEVVGLEGAIEMGQIYTKLKNA GRRLAKCSEITFHTTKTLPMQIDGE PWMQTPCTIKITHKNQMPMLMGPPP RSTNFFGFLSTRTRPLEQKLISEED LAANDILDYKDDDDKV | Purity : > 80% as determined by SDS-PAGE and Coomassie blue staining | Stability : Stable for 3 months from receipt of products under proper storage and handling conditions. | Storage : Store at -80 centigrade. Avoid repeated freeze-thaw cycles. | Concentration : 50 μg/mL as determined by BCA | Storage Buffer : 100 mM glycine, 25 mM Tris-HCl, pH 7.3.

Gene Information :
| Gene Name : DGKA diacylglycerol kinase, alpha 80kDa [ Homo sapiens (human) ] | Official Symbol : DGKA | Synonyms : DGKA; diacylglycerol kinase, alpha 80kDa; DAGK, DAGK1, diacylglycerol kinase, alpha (80kD); diacylglycerol kinase alpha; DGK alpha; DAG kinase alpha; diglyceride kinase alpha; 80 kDa diacylglycerol kinase; DAGK; DAGK1; DGK-alpha; MGC12821; MGC42356; | Gene ID : 1606 | mRNA Refseq : NM_201444 | Protein Refseq : NP_958852 | MIM : 125855 | UniProt ID : P23743

MedChemExpress (MCE) recombinant proteins include: cytokines, enzymes, growth factors, hormones, receptors, transcription factors, antibody fragments, etc. They are often essential for supporting cell growth, stimulating cell signaling pathways, triggering or inhibiting cell differentiation; and are useful tools for elucidating protein structure and function, understanding disease onset and progression, and validating pharmaceutical targets. At MedChemExpress (MCE), we strive to provide products with only the highest quality. Protein identity, purity and biological activity are assured by our robust quality control and assurance procedures.
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Author: Cholesterol Absorption Inhibitors