Recombinant Human DYRK3 Protein, GST-tagged

Specification :
| Description : This gene product belongs to the DYRK family of dual-specificity protein kinases that catalyze autophosphorylation on serine/threonine and tyrosine residues. The members of this family share structural similarity, however, differ in their substrate specificity, suggesting their involvement in different cellular functions. The encoded protein has been shown to autophosphorylate on tyrosine residue and catalyze phosphorylation of histones H3 and H2B in vitro. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008] | Source : Wheat Germ | Species : Human | Tag : GST | Molecular Mass : 88.22 kDa | AA Sequence : MKWKEKLGDGVYDTFMMIDETKCPP CSNVLCNPSEPPPPRRLNMTTEQFT GDHTQHFLDGGEMKVEQLFQEFGNR KSNTIQSDGISDSEKCSPTVSQGKS SDCLNTVKSNSSSKAPKVVPLTPEQ ALKQYKHHLTAYEKLEIINYPEIYF VGPNAKKRHGVIGGPNNGGYDDADG AYIHVPRDHLAYRYEVLKIIGKGSF GQVARVYDHKLRQYVALKMVRNEKR FHRQAAEEIRILEHLKKQDKTGSMN VIHMLESFTFRNHVCMAFELLSIDL YELIKKNKFQGFSVQLVHKFAQSIL QSLDALHKNKIIHCDLKPENILLKH HGRSSTKVIDFGSSCFEYQKLYTYI QSRFYRAPEIILGSRYSTPIDIWSF GCILAELLTGQPLFPGEDEGDQLAC MMELLGMPPPKLLEQSKRAKYFINS KGIPRYCSVTTQADGRVVLVGGRSR RGKKRGPPGSKDWGTALKGCDDYLF IEFLKRCLHWDPSARLTPAQALRHP WISKSVPRPLTTIDKVSGKRVVNPA SAFQGLGSKLPPVVGIANKLKANLM SETNGSIPLCSVLPKLIS | Applications : Kinase AssayEnzyme-linked Immunoabsorbent AssayWestern Blot (Recombinant protein)Antibody ProductionProtein Array | Notes : Best use within three months from the date of receipt of this protein. | Storage : Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing. | Storage Buffer : 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.