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Name :
Recombinant Human EGFR protein, His-tagged

Specification :
| Description : The protein encoded by this gene is a transmembrane glycoprotein that is a member of the protein kinase superfamily. This protein is a receptor for members of the epidermal growth factor family. EGFR is a cell surface protein that binds to epidermal growth factor. Binding of the protein to a ligand induces receptor dimerization and tyrosine autophosphorylation and leads to cell proliferation. Mutations in this gene are associated with lung cancer. | Source : Insect cells | Species : Human | Tag : His | Form : 50mM Tris-HCl pH8.0, 150mM NaCl, 20% glycerol. | Molecular Mass : 71 kDa | Protein length : Met1 – Ser645 | Purity : > 80% as determined by SDS-PAGE and Coomassie blue staining | Storage : Store at -80 centigrade. Avoid repeated freeze-thaw cycles. Stable for at least 3 months from receipt of products under proper storage and handling conditions. | Concentration : >50 ug/mL as determined by microplate BCA method

Gene Information :
| Gene Name : EGFR epidermal growth factor receptor [ Homo sapiens ] | Official Symbol : EGFR | Synonyms : EGFR; epidermal growth factor receptor; epidermal growth factor receptor (avian erythroblastic leukemia viral (v erb b) oncogene homolog) , ERBB; ERBB1; erythroblastic leukemia viral (v erb b) oncogene homolog (avian); proto-oncogene c-ErbB-1; cell growth inhibiting protein 40; cell proliferation-inducing protein 61; receptor tyrosine-protein kinase erbB-1; avian erythroblastic leukemia viral (v-erb-b) oncogene homolog; ERBB; HER1; mENA; PIG61; | Gene ID : 1956 | mRNA Refseq : NM_005228 | Protein Refseq : NP_005219 | MIM : 131550 | UniProt ID : P00533

MedChemExpress (MCE) recombinant proteins include: cytokines, enzymes, growth factors, hormones, receptors, transcription factors, antibody fragments, etc. They are often essential for supporting cell growth, stimulating cell signaling pathways, triggering or inhibiting cell differentiation; and are useful tools for elucidating protein structure and function, understanding disease onset and progression, and validating pharmaceutical targets. At MedChemExpress (MCE), we strive to provide products with only the highest quality. Protein identity, purity and biological activity are assured by our robust quality control and assurance procedures.
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Author: Cholesterol Absorption Inhibitors