Recombinant Human EIF2AK3 Protein, GST-tagged

Specification :
| Description : The protein encoded by this gene phosphorylates the alpha subunit of eukaryotic translation-initiation factor 2, leading to its inactivation, and thus to a rapid reduction of translational initiation and repression of global protein synthesis. This protein is thought to modulate mitochondrial function. It is a type I membrane protein located in the endoplasmic reticulum (ER), where it is induced by ER stress caused by malfolded proteins. Mutations in this gene are associated with Wolcott-Rallison syndrome. [provided by RefSeq, Sep 2015] | Source : Wheat Germ | Species : Human | Tag : GST | Molecular Mass : 36.63 kDa | AA Sequence : KWQEKMDEIWLKDESTDWPLSSPSP MDAPSVKIRRMDPFSTKEHIEIIAP SPQRSRSFSVGISCDQTSSSESQFS PLEFSGMDHEDISESVDAAYNLQDS | Applications : Enzyme-linked Immunoabsorbent AssayWestern Blot (Recombinant protein)Antibody ProductionProtein Array | Notes : Best use within three months from the date of receipt of this protein. | Storage : Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing. | Storage Buffer : 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.