Recombinant Human EIF2AK3 Protein, MYC/DDK-tagged

Specification :
| Description : The protein encoded by this gene phosphorylates the alpha subunit of eukaryotic translation-initiation factor 2, leading to its inactivation, and thus to a rapid reduction of translational initiation and repression of global protein synthesis. This protein is thought to modulate mitochondrial function. It is a type I membrane protein located in the endoplasmic reticulum (ER), where it is induced by ER stress caused by malfolded proteins. Mutations in this gene are associated with Wolcott-Rallison syndrome. | Source : HEK293 | Species : Human | Tag : MYC/DDK | Form : 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol. | Molecular Mass : 122.1 kDa | Purity : > 80% as determined by SDS-PAGE and Coomassie blue staining | Concentration : >50 ug/mL as determined by microplate BCA method