Recombinant Human ENG Protein, Myc/DDK-tagged, C13 and N15-labeled

Specification :
| Description : This gene encodes a homodimeric transmembrane protein which is a major glycoprotein of the vascular endothelium. This protein is a component of the transforming growth factor beta receptor complex and it binds to the beta1 and beta3 peptides with high affinity. Mutations in this gene cause hereditary hemorrhagic telangiectasia, also known as Osler-Rendu-Weber syndrome 1, an autosomal dominant multisystemic vascular dysplasia. This gene may also be involved in preeclampsia and several types of cancer. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. | Source : HEK293 | Species : Human | Tag : Myc/DDK | Molecular Mass : 67.78 kDa | AA Sequence : MDRGTLPLAVALLLASCSLSPTSLA ETVHCDLQPVGPERGEVTYTTSQVS KGCVAQAPNAILEVHVLFLEFPTGP SQLELTLQASKQNGTWPREVLLVLS VNSSVFLHLQALGIPLHLAYNSSLV TFQEPPGVNTTELPSFPKTQILEWA AERGPITSAAELNDPQSILLRLGQA QGSLSFCMLEASQDMGRTLEWRPRT PALVRGCHLEGVAGHKEAHILRVLP GHSAGPRTVTVKVELSCAPGDLDAV LILQGPPYVSWLIDANHNMQIWTTG EYSFKIFPEKNIRGFKLPDTPQGLL GEARMLNASIVASFVELPLASIVSL HASSCGGRLQTSPAPIQTTPPKDTC SPELLMSLIQTKCADDAMTLVLKKE LVAHLKCTITGLTFWDPSCEAEDRG DKFVLRSAYSSCGMQVSASMISNEA VVNILSSSSPQRKKVHCLNMDSLSF QLGLYLSPHFLQASNTIEPGQQSFV QVRVSPSVSEFLLQLDSCHLDLGPE GGTVELIQGRAAKGNCVSLLSPSPE GDPRFSFLLHFYTVPIPKTGTLSCT VALRPKTGSQDQEVHRTVFMRLNII SPDLSGCTSKGLVLPAVLGITFGAF LIGALLTAALWYIYSHTREYPRPPQ SGPSGPTRTRRLEQKLISEEDLAAN DILDYKDDDDKV | Purity : > 80% as determined by SDS-PAGE and Coomassie blue staining | Stability : Stable for 3 months from receipt of products under proper storage and handling conditions. | Storage : Store at -80 centigrade. Avoid repeated freeze-thaw cycles. | Concentration : 50 μg/mL as determined by BCA | Storage Buffer : 100 mM glycine, 25 mM Tris-HCl, pH 7.3.