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Name :
Recombinant Human EPCAM protein, His-tagged

Specification :
| Description : TACSTD1, also known as tumor-associated calcium signal transducer 1, is a membrane glycoprotein expressed on adenomatous and simple epithelia, where it is involved in homophilic adhesion at the basolateral membrane. It may act as a physical homophilic interaction molecule between intestinal epithelial cells (IECs) and intraepithelial lymphocytes (IELs) at the mucosal epithelium for providing immunological barrier as a first line of defense against mucosal infection. It plays a role in embryonic stem cells proliferation and differentiation. | Source : Insect cell | Species : Human | Tag : His | Form : Liquid. In Phosphate Buffered Saline (pH 7.4) containing 10% glycerol. | Molecular Mass : 28.2kDa (248aa)28-40kDa (SDS-PAGE under reducing conditions) | AA Sequence : QEECVCENYK LAVNCFVNNN RQCQCTSVGA QNTVICSKLA AKCLVMKAEM NGSKLGRRAK PEGALQNNDG LYDPDCDESG LFKAKQCNGTSTCWCVNTAG VRRTDKDTEI TCSERVRTYW IIIELKHKAR EKPYDSKSLR TALQKEITTR YQLDPKFITS ILYENNVITI DLVQNSSQKTQNDVDIADVA YYFEKDVKGE SLFHSKKMDL TVNGEQLDLD PGQTLIYYVD EKAPEFSMQG LKHHHHHH | Endotoxin : | Purity : >95% by SDS – PAGE | Storage : Can be stored at +4 centigrade short term (1-2 weeks). For long term storage, aliquot and store at -20 centigrade or -70 centigrade. Avoid repeated freezing and thawing cycles. | Concentration : 1mg/ml (determined by Absorbance at 280nm)

Gene Information :
| Gene Name : EPCAM epithelial cell adhesion molecule [ Homo sapiens ] | Official Symbol : EPCAM | Synonyms : ESA; KSA; M4S1; MK-1; DIAR5; EGP-2; EGP40; KS1/4; MIC18; TROP1; EGP314; HNPCC8; TACSTD1; adenocarcinoma-associated antigen; cell surface glycoprotein Trop-1; epithelial glycoprotein 314; human epithelial glycoprotein-2; major gastrointestinal tumor-associated protein GA733-2; membrane component, chromosome 4, surface marker (35kD glycoprotein); tumor-associated calcium signal transducer 1 | Gene ID : 4072 | mRNA Refseq : NM_002354 | Protein Refseq : NP_002345 | MIM : 185535 | UniProt ID : P16422 | Chromosome Location : 2p21 | Function : cadherin binding involved in cell-cell adhesion; protein binding; protein complex binding

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Author: Cholesterol Absorption Inhibitors