Recombinant Human EPCAM Protein, His-tagged

Specification :
| Description : Epithelial cell adhesion and activating molecule (EpCAM/CD326) is a transmembrane glycoprotein that mediates Ca2+-independent, homophilic adhesions on the basolateral surface of most epithelial cells. EpCAM is not expressed in adult squamous epithelium, but it is highly expressed in adeno and squamous cell carcinomas. Research studies identified EpCAM as one of the first tumor-associated antigens, and it has long been a marker of epithelial and tumor tissue. Investigators have shown that EpCAM is highly expressed in cancer cells. | Source : E. coli | Species : Human | Tag : His | Molecular Mass : ~32 kDa | AA Sequence : QEECVCENYKLAVNCFVNNNRQCQC TSVGAQNTVICSKLAAKCLVMKAEM NGSKLGRRAKPEGALQNNDGLYDPD CDESGLFKAKQCNGTSMCWCVNTAG VRRTDKDTEITCSERVRTYWIIIEL KHKAREKPYDSKSLRTALQKEITTR YQLDPKFITSILYENNVITIDLVQN SSQKTQNDVDIADVAYYFEKDVKGE SLFHSKKMDLTVNGEQLDLDPGQTL IYYVDEKAPEFSMQGLK | Purity : Transferred into competent cells and the supernatant was purified by NI column affinity chromatography and the purity is > 85% (by SDS-PAGE). | Notes : For research use only, not for use in diagnostic procedure. | Storage : Store at 4 centigrade short term. Aliquot and store at -20 centigrade long term. Avoid freeze-thaw cycles. | Storage Buffer : PBS, 4M Urea, pH7.4