Name :
Recombinant Human FASLG Protein (Gln103-Leu281), His tagged
Specification :
| Description : Cytokine that binds to TNFRSF6/FAS, a receptor that transduces the apoptotic signal into cells. Involved in cytotoxic T-cell-mediated apoptosis, natural killer cell-mediated apoptosis and in T-cell development. Initiates fratricidal/suicidal activation-induced cell death (AICD) in antigen-activated T-cells contributing to the termination of immune responses. TNFRSF6/FAS-mediated apoptosis has also a role in the induction of peripheral tolerance. Binds to TNFRSF6B/DcR3, a decoy receptor that blocks apoptosis. | Source : E. coli | Species : Human | Tag : His | Molecular Mass : 22.34 kDa | Protein Length : Gln103-Leu281 | Purity : >90 % as determined by SDS-PAGE. | Notes : For research use only. | Storage : Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8 centigrade for one week. Store at -20 to -80 centigrade for twelve months from the date of receipt. | Storage Buffer : Supplied as solution form in PBS pH 7.5 or lyophilized from PBS pH 7.5. | Reconstitution : Reconstitute in sterile water for a stock solution. | Shipping : In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Gene Information :
| Gene Name : FASLG Fas ligand (TNF superfamily, member 6) [ Homo sapiens (human) ] | Official Symbol : FASLG | Synonyms : FASLG; Fas ligand (TNF superfamily, member 6); APT1LG1, TNFSF6, tumor necrosis factor (ligand) superfamily, member 6; tumor necrosis factor ligand superfamily member 6; CD178; FasL; APTL; CD95 ligand; fas antigen ligand; apoptosis antigen ligand; apoptosis (APO-1) antigen ligand 1; tumor necrosis factor (ligand) superfamily, member 6; FASL; CD95L; CD95-L; TNFSF6; APT1LG1; | Gene ID : 356 | mRNA Refseq : NM_000639 | Protein Refseq : NP_000630 | MIM : 134638 | UniProt ID : P48023
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