Recombinant Human FASLG Protein, GST-tagged

Specification :
| Description : This gene is a member of the tumor necrosis factor superfamily. The primary function of the encoded transmembrane protein is the induction of apoptosis triggered by binding to FAS. The FAS/FASLG signaling pathway is essential for immune system regulation, including activation-induced cell death (AICD) of T cells and cytotoxic T lymphocyte induced cell death. It has also been implicated in the progression of several cancers. Defects in this gene may be related to some cases of systemic lupus erythematosus (SLE). Alternatively spliced transcript variants have been described. [provided by RefSeq, Nov 2014] | Source : Wheat Germ | Species : Human | Tag : GST | Molecular Mass : 56.65 kDa | AA Sequence : MQQPFNYPYPQIYWVDSSASSPWAP PGTVLPCPTSVPRRPGQRRPPPPPP PPPLPPPPPPPPLPPLPLPPLKKRG NHSTGLCLLVMFFMVLVALVGLGLG MFQLFHLQKELAELRESTSQMHTAS SLEKQIGHPSPPPEKKELRKVAHLT GKSNSRSMPLEWEDTYGIVLLSGVK YKKGGLVINETGLYFVYSKVYFRGQ SCNNLPLSHKVYMRNSKYPQDLVMM EGKMMSYCTTGQMWARSSYLGAVFN LTSADHLYVNVSELSLVNFEESQTF FGLYKL | Applications : Enzyme-linked Immunoabsorbent AssayWestern Blot (Recombinant protein)Antibody ProductionProtein Array | Notes : Best use within three months from the date of receipt of this protein. | Storage : Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing. | Storage Buffer : 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.