Name :
Recombinant Human Fc fragment of IgG, low affinity IIb, receptor (CD32), His-tagged
Specification :
| Description : FCGR2B is a low affinity receptor for the Fc region of immunoglobulin gamma complexes. The protein is involved in the phagocytosis of immune complexes and in the regulation of antibody production by B-cells. Variations in this gene may increase susceptibilty to systemic lupus erythematosus (SLE). Several transcript variants encoding different have been found for this gene. Recombinant human FCGR2B protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. | Source : E.coli | Species : Human | Tag : His-tag | Form : Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 0.15M NaCl, 30% glycerol,1mM DTT | Molecular Mass : 22.0 kDa (197aa) confirmed by MALDI-TOF | AA Sequence : MGSSHHHHHH SSGLVPRGSH MGSHMAPPKA VLKLEPQWIN VLQEDSVTLT CRGTHSPESD SIQWFHNGNL IPTHTQPSYR FKANNNDSGE YTCQTGQTSL SDPVHLTVLS EWLVLQTPHL EFQEGETIVL RCHSWKDKPL VKVTFFQNGK SKKFSRSDPN FSIPQANHSH SGDYHCTGNI GYTLYSSKPV TITVQAP | Purity : >95% by SDS – PAGE | Storage : Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles. | Concentration : 0.5 mg/ml (determined by Bradford assay)
Gene Information :
| Gene Name : FCGR2B Fc fragment of IgG, low affinity IIb, receptor (CD32) [ Homo sapiens ] | Official Symbol : FCGR2B | Synonyms : FCGR2B; Fc fragment of IgG, low affinity IIb, receptor (CD32); Fc fragment of IgG, low affinity IIb, receptor for (CD32) , FCG2, FCGR2; low affinity immunoglobulin gamma Fc region receptor II-b; CD32; CD32B; CDw32; fcRII-b; Fc gamma RIIb; fc-gamma-RIIb; fc-gamma RII-b; IgG Fc receptor II-b; Fc fragment of IgG, low affinity II, receptor for (CD32); Fc fragment of IgG, low affinity IIb, receptor for (CD32); FCG2; FCGR2; IGFR2; | Gene ID : 2213 | mRNA Refseq : NM_001002273 | Protein Refseq : NP_001002273 | MIM : 604590 | UniProt ID : P31994 | Chromosome Location : 1q23 | Pathway : Adaptive Immune System, organism-specific biosystem; B Cell Receptor Signaling Pathway, organism-specific biosystem; B cell receptor signaling pathway, organism-specific biosystem; B cell receptor signaling pathway, conserved biosystem; BCR signaling pathway, organism-specific biosystem; Fc gamma R-mediated phagocytosis, organism-specific biosystem; Fc gamma R-mediated phagocytosis, conserved biosystem; | Function : IgG binding; protein binding; receptor activity;
Related category websites: https://www.medchemexpress.com/recombinant-proteins.html
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