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Name :
Recombinant Human FCER2, StrepII-tagged

Specification :
| Description : CD23 is a B-cell specific antigen, and a low-affinity receptor for IgE. It has essential roles in B cell growth and differentiation, and the regulation of IgE production. This protein is a single-pass type II membrane protein, but also exists as a soluble secreted form, then functioning as a potent mitogenic growth factor. | Source : Human Cells | Species : Human | Tag : StrepII | Form : Lyophilized from sterile 0.2μm filtered solution in 0.3X PBS with 10% Trehalose (carrier-free). | Protein length : 48-321, 274 a.a. | AA Sequence : DTTQSLKQLEERAARNVSQVSKNLE SHHGDQMAQKSQSTQISQELEELRA EQQRLKSQDLELSWNLNGLQADLSS FKSQELNERNEASDL LERLREEVTKLRMELQVSSGFVCNT CPEKWINFQRKCYYFGKGTKQWVHA RYACDDMEGQLVSIHSPEEQDFLTK HASHTGSWIGLRNLDLKGEFIWVD GSHVDYSNWAPGEPTSRSQGEDCVM MRGSGRWNDAFCDRKLGAWVCDRLA TCTPPASEGSAESMGPDSRPDPDGR LPTPSAPLHS | Endotoxin : | Purity : ~90% pure by SDS-PAGE | Storage : 12 months at -20°C as supplied; 1 month at 4°C after reconstitution. Avoid freeze/thaw cycles. | Reconstitution : Centrifuge the vial prior to opening. Reconstitute in PBS to a concentration of 0.1 mg/ml.

Gene Information :
| Gene Name : FCER2 Fc fragment of IgE, low affinity II, receptor for (CD23) [ Homo sapiens ] | Official Symbol : FCER2 | Synonyms : FCER2; Fc fragment of IgE, low affinity II, receptor for (CD23); CD23A, Fc fragment of IgE, low affinity II, receptor for (CD23A) , FCE2; low affinity immunoglobulin epsilon Fc receptor; CD23; CLEC4J; BLAST-2; CD23 antigen; fc-epsilon-RII; lymphocyte IgE receptor; immunoglobulin E-binding factor; C-type lectin domain family 4, member J; FCE2; CD23A; IGEBF; | Gene ID : 2208 | mRNA Refseq : NM_001207019 | Protein Refseq : NP_001193948 | MIM : 151445 | UniProt ID : P06734 | Chromosome Location : 19p13.3 | Pathway : Hematopoietic cell lineage, organism-specific biosystem; Hematopoietic cell lineage, conserved biosystem; IL-3 Signaling Pathway, organism-specific biosystem; IL4-mediated signaling events, organism-specific biosystem; | Function : IgE binding; binding; integrin binding; metal ion binding; receptor activity; sugar binding;

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Author: Cholesterol Absorption Inhibitors